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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowMiscellaneous Glutamate
Cat.No. Product Name
2049 Anti-glutamate receptor d1/2
(Rabbit polyclonal IgG)
Immunoblot IB: Rat brain homogenate probed with anti-glutamate receptor δ1/2 (1 μg/ml)
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glutamate receptor delta1 / 2, Anti-

Specificity and cross reactivity:

Recognises both rat glutamate receptor δ1 and δ2 which exhibit some sequence similarity in their C-termini; migrates at a band of ~ 115 kDa. Also predicted to cross-react with mouse and human homologues.

Immunogen:

KLH conjugated synthetic peptide ([C]-QPTPTLGLNLGNDPDRGTSI) corresponding to C-terminal amino acids 988-1007 of rat precursor glutamate receptor δ2 (Accession No. Q63226) with a cysteine added at the N-terminus of the peptide. 50 μg of immunogen is provided with the antibody as a blocking peptide and can also be purchased separately (Cat. No. 2114).

Applications:

IB

Resources:

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    Certificate of Analysis / MSDS:

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    References:

    Mayat et al (1995) Immunoprecipitation, immunoblotting, and immunocytochemistry studies suggest that glutamate receptor δ subunits form novel postsynaptic receptor complexes. J.Neurosci. 15 2533. Landsend et al (1997) Differential localization of δ glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses. J.Neurosci. 17 834.
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    Keywords: Glutamate Receptor Delta1 / 2, Anti-, Ligand-gated Ion Channels, Antibody Recognising Rat Glutamate Receptor D1 & D2 Subunits, Tocris Bioscience
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