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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowOther
Cat.No. Product Name
2053

Anti-phospho-NR1 (Ser897)

(Rabbit polyclonal IgG)
Immunoblot IB: Rat brain microsome extract probed with anti-phospho-NR1 (Ser897) at 1:500 dilution (lane 1), or phosphatase treated (lane 2). Arrow indicates phospho-NR1 (~ 120 kDa).
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NR1 (Ser897), Anti-phospho-

Specificity and cross reactivity:

Recognises rat NR1 phosphorylated on serine 897 and migrates at a band of ~ 120 kDa. Also recognises NR1 that is dually phosphorylated on serine 896 and 897 and predicted to cross-react with mouse and human homologues.

Immunogen:

Thyroglobulin conjugated synthetic peptide ([K]-FKRRRS(pS)KDTST) corresponding to amino acids 891-902 of rat precursor NMDA receptor subunit 1 (Accession No. P35439) with a phosphorylated serine at position 897, and a lysine added at the N-terminus of the peptide.

Applications:

IB

Resources:

  • Certificate of Analysis / MSDS:

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    References:

    Tingley et al (1997) Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J.Biol.Chem. 272 5157.
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    Keywords: NR1 (Ser897), Anti-phospho-, NMDA Selective, Antibody Recognising Rat NR1 Subunits Phosphorylated At Ser897, NR1(Ser897), Anti-phospho-, Other, Glutamate (Ionotropic) Receptors, Ligand-gated Ion Channels, Ion Channels, Tocris Bioscience

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