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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowAMPA SelectivearrowOther
Cat.No. Product Name
2041 Anti-phospho-GluR1 (Ser831)
(Rabbit polyclonal IgG)
Immunoblot IB: Rat brain microsomal preparation was probed with Anti-phospho-GluR1 (Ser831) (1:500); no peptide (lane 1) and immunizing phosphopeptide (lane 2). Arrow indicates pGluR1 (Ser831),  (~ 106 kDa).
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GluR1 (Ser831), Anti-phospho-

Specificity and cross reactivity:

Recognises rat GluR1 phosphorylated on serine 831 and migrates at a band of ~ 106 kDa. Also predicted to cross-react with mouse and human homologues.

Immunogen:

Thyroglobulin-conjugated synthetic peptide (LIPQQ(pS)INEAI-[K]) corresponding to amino acids 826-836 of rat mature GluR1 (Accession No. P19490), with a phosphorylated serine at position 831, and a lysine added to the C-terminus for conjugation.

Applications:

IB

Resources:

    		•

    Certificate of Analysis / MSDS:

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    References:

    Martin et al (1993) AMPA glutamate receptor subunits are differentially distributed in rat brain. Neuroscience 3 327. Barria et al (1997) Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor. J.Biol.Chem. 272 32727. Roche et al (1996) Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron 16 1179.
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    Keywords: GluR1 (Ser831), Anti-phospho-, Ligand-gated Ion Channels, Antibody Recognising Rat GluR1 Subunits Phosphorylated At Ser831, Tocris Bioscience
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