R&D Systems Inc. Tocris Bioscience Boston Biochem

HMG-CoA Reductase

More Information »3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) catalyzes the rate limiting step in cholesterol biosynthesis - conversion of 3-hydroxy-3-methyl-glutaryl-CoA to mevalonic acid. HMG-CoA reductase is a transmembrane enzyme, bound to endoplasmic reticulum.

HMG-CoA Reductase Products

Inhibitors
Cat.No.
Product Name / Activity
3776 Atorvastatin hemicalcium salt
HMG-CoA reductase inhibitor
3309 Fluvastatin sodium
HMG-CoA reductase inhibitor
1530 Lovastatin
HMG-CoA reductase inhibitor
1526 Mevastatin
HMG-CoA reductase inhibitor
4942 Pitavastatin calcium
HMG-CoA reductase inhibitor
2318 Pravastatin sodium salt
HMG-CoA reductase inhibitor
1965 Simvastatin
HMG-CoA reductase inhibitor
Other
Cat.No.
Product Name / Activity
2969 SR 12813
Enhances HMG-CoA reductase degradation. Also PXR agonist

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