HMG-CoA Reductase

More Information »3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) catalyzes the rate limiting step in cholesterol biosynthesis - conversion of 3-hydroxy-3-methyl-glutaryl-CoA to mevalonic acid. HMG-CoA reductase is a transmembrane enzyme, bound to endoplasmic reticulum.

HMG-CoA Reductase Products

Inhibitors
Cat.No.	Product Name / Activity
3776	Atorvastatin hemicalcium salt
	HMG-CoA reductase inhibitor
3309	Fluvastatin sodium
	HMG-CoA reductase inhibitor
1530	Lovastatin
	HMG-CoA reductase inhibitor
1526	Mevastatin
	HMG-CoA reductase inhibitor
2318	Pravastatin sodium salt
	HMG-CoA reductase inhibitor
1965	Simvastatin
	HMG-CoA reductase inhibitor
Other
Cat.No.	Product Name / Activity
2969	SR 12813
	Enhances HMG-CoA reductase degradation. Also PXR agonist