R&D Systems Inc. Tocris Bioscience Boston Biochem

Formyl Peptide Receptors

More Information »The formyl peptide receptor family, FPR1, FPR2 and FPR3 (formerly FPR, FPRL1 and FPRL2 respectively) are Gi-protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes. FPRs are involved in antibacterial host defence and inflammation.

Formyl Peptide Receptor Products

Agonists
Cat.No.
Product Name / Activity
1921 N-Formyl-Met-Leu-Phe
Endogenous FPR1 agonist
2826 FPR A14
FPR agonist
3537 MMK 1
Potent and selective FPR2 agonist
1799 WKYMVM
Selective FPR2 and FPR3 receptor agonist
1800 WKYMVm
FPR1, FPR2 and FPR3 receptor agonist
Antagonists
Cat.No.
Product Name / Activity
3730 Boc-MLF
FPR1 antagonist
4611 PBP 10
Selective FPR2 antagonist; cell permeable
2262 WRW4
Selective FPR2 antagonist
Ligands
Cat.No.
Product Name / Activity
3231 Ac9-25
Annexin I N-terminal peptide. Acts as a FPR1 ligand
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7-TM Receptor Signaling

Written by T. Kenakin et al

7-TM Poster

'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy

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New Product Guide

NPG

Highlights over 130 new products added in 2012. Request a copy or view PDF today.

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20% Discount*

Potent, selective LRRK2 inhibitor

Potent LRRK2 inhibitor now available from Tocris Bioscience

Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.

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