R&D Systems Inc. Tocris Bioscience Boston Biochem

PI 3-kinase

More Information »PI 3-Kinases (phosphoinositide 3-kinases, PI 3-Ks) are family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of cell functions including proliferation and survival.

PI 3-kinase Products

Inhibitors
Cat.No.
Product Name / Activity
3671 AS 252424
Selective inhibitor of PI 3-kinase γ
3578 AS 605240
Potent and selective PI 3-kinase γ (PI3-Kγ) inhibitor
4839 AZD 6482
Potent and selective PI 3-Kβ inhibitor
3606 BAG 956
Dual PI 3-kinase and PDK1 inhibitor
4674 CZC 24832
Selective inhibitor of PI 3-kinase γ
4026 GSK 1059615
Potent PI 3-kinase inhibitor
4840 KU 0060648
Dual DNA-PK and PI 3-K inhibitor
1130 LY 294002 hydrochloride
Selective PI 3-kinase inhibitor
2418 LY 303511
Negative control of LY 294002 (Cat. No. 1130)
3977 3-Methyladenine
Class III PI 3-kinase inhibitor; also inhibits autophagy
4820 PF 04691502
Potent and selective dual PI 3-K/mTOR inhibitor
4823 PF 05212384
Potent and selective dual PI 3-K/mTOR inhibitor
2930 PI 103 hydrochloride
Inhibitor of PI 3-kinase, mTOR and DNA-PK
2814 PI 828
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
3894 PP 121
Dual kinase inhibitor; inhibits PI 3-K family kinases
1125 Quercetin
Non-selective PI 3-kinase inhibitor
4264 TG 100713
PI 3-kinase inhibitor
1232 Wortmannin
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
Activators
Cat.No.
Product Name / Activity
1983 740 Y-P
Cell-permeable PI 3-kinase activator
Other
Cat.No.
Product Name / Activity
5126 iMDK
Potent suppressor of MDK expression; antitumor
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

divider line

Kinases Product Listing

Kinases Product Listing

Highlights over 350 products for kinase research. Request a copy or view PDF today.

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Some of the most potent
kinase inhibitors all on one plate

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Calcium Imbalance and Neuroprotective Targets

Written by E. Besancon et al

Neuroprotection Poster

'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.

divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

divider line

New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

divider line

Bio-Techne Events

British Society for Cardiovascular Research Autumn Meeting

British Society for Cardiovascular Research Autumn Meeting

September 8 - 9, 2014

Reading, UK