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Bradykinin Receptors
More Information »Bradykinin and related kinins are a family of small peptides which act as mediators of pain and inflammation. They exert a variety of biological effects on the endothelium and peripheral circulation through their action on two bradykinin receptor subtypes: B1 and B2.
Bradykinin Receptor Products
Agonists |
|
Cat.No. |
Product Name / Activity |
| 2371 | Bombinakinin M |
| Potent bradykinin receptor agonist | |
| 3004 | Bradykinin |
| Endogenous agonist at bradykinin receptors (B2 > B1) | |
| 3230 | Sar-[D-Phe8]-des-Arg9-Bradykinin |
| Potent and selective B1 agonist | |
| 3005 | [Des-Arg9]-Bradykinin |
| Bradykinin receptor agonist (B1 > B2) | |
| 3229 | [Phe8Ψ(CH-NH)-Arg9]-Bradykinin |
| Selective B2 agonist | |
| 3227 | Lys-Bradykinin |
| Potent bradykinin receptor agonist (B2 > B1) | |
| 3225 | Lys-[Des-Arg9]Bradykinin |
| Selective B1 agonist | |
Antagonists |
|
Cat.No. |
Product Name / Activity |
| 3014 | HOE 140 |
| Potent and selective B2 antagonist | |
| 3978 | MEN 11270 |
| Selective B2 antagonist; analog of HOE 140 (Cat. No. 3014) | |
| 1697 | Noscapine hydrochloride |
| Bradykinin antagonist. Also tubulin inhibitor | |
| 3407 | R 715 |
| Potent and selective B1 antagonist | |
| 3226 | R 892 |
| Potent and selective B1 antagonist | |
| 1057 | WIN 64338 hydrochloride |
| Bradykinin B2 antagonist | |
Other |
|
Cat.No. |
Product Name / Activity |
| 2370 | Bombinakinin-GAP |
| Bioactive, bradykinin-related peptide | |
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Regulation of Vascular Reactivity by GPCRs
Written by J.J. Maguire and A.P. Davenport
'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity.
7-TM Receptor Signaling
Written by T. Kenakin et al
'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy
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