Glycogen Synthase Kinase 3

More Information »Glycogen synthase kinase 3 (GSK-3) is a serine-threonine kinase with two isoforms (α and β), that was originally discovered as an important enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cellular division, proliferation, motility and survival.

Glycogen Synthase Kinase 3 Products

Product Name / Activity
4083 3F8
Potent and selective GSK-3β inhibitor
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
3966 AR-A 014418
Selective GSK-3 inhibitor
3194 BIO
Potent, selective GSK-3 inhibitor
3874 BIO-acetoxime
Selective GSK-3α/β inhibitor
4423 CHIR 99021
Highly selective GSK-3 inhibitor
4953 CHIR 99021 trihydrochloride
Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
1532 10Z-Hymenialdisine
Pan kinase inhibitor; potently inhibits GSK-3β
1813 Indirubin-3'-oxime
GSK-3β inhibitor. Also inhibits other protein kinases
1398 Kenpaullone
GSK-3 inhibitor. Also inhibits cdks
2235 L803
Substrate-competitive inhibitor of GSK-3
2256 L803-mts
Selective inhibitor of GSK-3
4740 Lithium carbonate
Mood stabilizer; inhibits GSK-3 in vivo
3873 MeBIO
Inactive analog of BIO (Cat. No. 3194)
1937 NSC 693868
GSK-3 inhibitor. Also inhibits cdks
1616 SB 216763
Potent, selective GSK-3 inhibitor
1617 SB 415286
Potent, selective GSK-3 inhibitor
4353 TC-G 24
Potent and selective GSK-3β inhibitor
3869 TCS 2002
Potent GSK-3β inhibitor
4221 TCS 21311
GSK-3β inhibitor. Also inhibits PKC and JAK3
3835 TWS 119
GSK-3β inhibitor; induces neuronal differentiation in ESCs
Product Name / Activity
1802 2B-(SP)
Selective GSK-3 phosphopeptide substrate
1352 Phospho-Glycogen Synthase Peptide-2 (substrate)
GSK-3 substrate (synthetic)
Product Name / Activity
2236 TCS 183
Fragment 1-13 of GSK-3β sequence
2320 TCS 184
Scrambled control peptide for use with TCS 183 (Cat. No. 2236)
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