R&D Systems Inc. Tocris Bioscience Boston Biochem

Glycogen Synthase Kinase 3

More Information »Glycogen synthase kinase 3 (GSK-3) is a serine-threonine kinase with two isoforms (α and β), that was originally discovered as an important enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cellular division, proliferation, motility and survival.

Glycogen Synthase Kinase 3 Products

Inhibitors
Cat.No.
Product Name / Activity
4083 3F8
Potent and selective GSK-3β inhibitor
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
3966 AR-A 014418
Selective GSK-3 inhibitor
3194 BIO
Potent, selective GSK-3 inhibitor
3874 BIO-acetoxime
Selective GSK-3α/β inhibitor
4423 CHIR 99021
Highly selective GSK-3 inhibitor
4953 CHIR 99021 trihydrochloride
Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
1835 FRATide
GSK-3 inhibitor
1532 10Z-Hymenialdisine
Pan kinase inhibitor; potently inhibits GSK-3β
1813 Indirubin-3'-oxime
GSK-3β inhibitor. Also inhibits other protein kinases
1398 Kenpaullone
GSK-3 inhibitor. Also inhibits cdks
2235 L803
Substrate-competitive inhibitor of GSK-3
2256 L803-mts
Selective inhibitor of GSK-3
4740 Lithium carbonate
Mood stabilizer; inhibits GSK-3 in vivo
3873 MeBIO
Inactive analog of BIO (Cat. No. 3194)
1937 NSC 693868
GSK-3 inhibitor. Also inhibits cdks
1616 SB 216763
Potent, selective GSK-3 inhibitor
1617 SB 415286
Potent, selective GSK-3 inhibitor
4353 TC-G 24
Potent and selective GSK-3β inhibitor
3869 TCS 2002
Potent GSK-3β inhibitor
4221 TCS 21311
GSK-3β inhibitor. Also inhibits PKC and JAK3
3835 TWS 119
GSK-3β inhibitor; induces neuronal differentiation in ESCs
Substrates
Cat.No.
Product Name / Activity
1802 2B-(SP)
Selective GSK-3 phosphopeptide substrate
1352 Phospho-Glycogen Synthase Peptide-2 (substrate)
GSK-3 substrate (synthetic)
Other
Cat.No.
Product Name / Activity
2236 TCS 183
Fragment 1-13 of GSK-3β sequence
2320 TCS 184
Scrambled control peptide for use with TCS 183 (Cat. No. 2236)
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

divider line

Kinases Product Listing

Kinases Product Listing

Highlights over 350 products for kinase research. Request a copy or view PDF today.

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Some of the most potent
kinase inhibitors all on one plate

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development.

divider line

The Neurobiology of Alzheimer's Disease

Written by Alan Palmer

Alzheimer's Poster

'The Neurobiology of Alzheimer's Disease' summarizes structural and functional changes observed in the progression of AD.

divider line

New Product Guide

NPG

Highlights over 130 new products added in the second half of 2013. Request a copy or view PDF today.

divider line

Tocris Events

Immunology 2014

Immunology 2014

May 2-6, 2014

Pittsburgh, Pennsylvania

Booth Number: 523