Glycogen Synthase Kinase 3

More Information »Glycogen synthase kinase 3 (GSK-3) is a serine-threonine kinase with two isoforms (α and β), that was originally discovered as an important enzyme in glycogen metabolism. GSK-3 was subsequently shown to function in cellular division, proliferation, motility and survival.

Glycogen Synthase Kinase 3 Products

Inhibitors
Cat.No.	Product Name / Activity
4083	3F8
	Potent and selective GSK-3β inhibitor
4431	A 1070722
	Highly potent, selective GSK-3 inhibitor
3966	AR-A 014418
	Selective GSK-3 inhibitor
3194	BIO
	Potent, selective GSK-3 inhibitor
3874	BIO-acetoxime
	Selective GSK-3α/β inhibitor
4423	CHIR 99021
	Highly selective GSK-3 inhibitor
1835	FRATide
	GSK-3 inhibitor
1532	10Z-Hymenialdisine
	Pan kinase inhibitor; potently inhibits GSK-3β
1813	Indirubin-3'-oxime
	GSK-3β inhibitor. Also inhibits other protein kinases
1398	Kenpaullone
	GSK-3 inhibitor. Also inhibits cdks
2235	L803
	Substrate-competitive inhibitor of GSK-3
2256	L803-mts
	Selective inhibitor of GSK-3
3873	MeBIO
	Inactive analog of BIO (Cat. No. 3194)
1937	NSC 693868
	GSK-3 inhibitor. Also inhibits cdks
1616	SB 216763
	Potent, selective GSK-3 inhibitor
1617	SB 415286
	Potent, selective GSK-3 inhibitor
4353	TC-G 24
	Potent and selective GSK-3β inhibitor
3869	TCS 2002
	Potent GSK-3β inhibitor
4221	TCS 21311
	GSK-3β inhibitor. Also inhibits PKC and JAK3
3835	TWS 119
	GSK-3β inhibitor; induces neuronal differentiation in ESCs
Substrates
Cat.No.	Product Name / Activity
1802	2B-(SP)
	Selective GSK-3 phosphopeptide substrate
1352	Phospho-Glycogen Synthase Peptide-2 (substrate)
	GSK-3 substrate (synthetic)
Other
Cat.No.	Product Name / Activity
2236	TCS 183
	Fragment 1-13 of GSK-3β sequence
2320	TCS 184
	Scrambled control peptide for use with TCS 183 (Cat. No. 2236)

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