TRPV

More Information »Vanilloids are a group of compounds, structurally related to capsaicin, thought to exert their actions via vanilloid receptors. The vanilloid receptor family (TRPV) is a member of the transient receptor potential (TRP) superfamily of ion channels, and have six members (TRPV1-6).

TRPV Products

Agonists
Cat.No.	Product Name / Activity
1116	AM 404
	Vanilloid receptor agonist. Also anandamide transport inhibitor
1685	AM 404 (in Tocrisolve™ 100)
	Vanilloid receptor agonist. Also anandamide transport inhibitor (in water-soluble emulsion)
1339	Anandamide
	Endogenous CB and TRPV1 receptor agonist
1017	Anandamide (in Tocrisolve™ 100)
	Endogenous CB and TRPV1 receptor agonist (in water-soluble emulsion)
1354	Arvanil
	Potent TRPV1 (VR1) and CB₁ agonist/anandamide transport inhibitor
0462	(E)-Capsaicin
	Prototypic vanilloid receptor agonist
1556	6'-Iodoresiniferatoxin
	High affinity TRPV1 agonist/partial agonist
1568	NADA
	Endogenous TRPV1 agonist. Also CB₁ agonist
1641	OLDA
	Potent, selective endogenous TRPV1 agonist
0934	Olvanil
	Potent vanilloid receptor agonist
1466	PPAHV
	Non-pungent vanilloid receptor agonist
1137	Resiniferatoxin
	Potent vanilloid receptor agonist
3745	RN 1747
	Selective TRPV4 agonist
Antagonists
Cat.No.	Product Name / Activity
4319	A 784168
	Potent and selective TRPV1 antagonist
2316	AMG 9810
	Potent and selective, competitive antagonist of TRPV1
2836	Arachidonyl serotonin
	Dual FAAH inhibitor/TRPV1 antagonist
3875	BCTC
	TRPV1 antagonist
0464	Capsazepine
	Vanilloid receptor antagonist. Also activator of ENaCδ
4100	HC 067047
	Potent and selective TRPV4 antagonist
1975	6-Iodonordihydrocapsaicin
	Potent, competitive vanilloid receptor antagonist
1362	5'-Iodoresiniferatoxin
	Potent, silent TRPV1 antagonist
3361	JNJ 17203212
	Reversible, competitive and potent TRPV1 antagonist
1577	L-R₄W₂
	TRPV1 antagonist peptide
3746	RN 1734
	Selective TRPV4 antagonist
1439	Ruthenium Red
	Blocks capsaicin-activated cation channels
1615	SB 366791
	Potent, selective, competitive TRPV1 (VR1) antagonist
3265	SB 452533
	Potent TRPV1 receptor antagonist
4729	α-Spinasterol
	TRPV1 antagonist; displays in vivo activity
Ligand Sets
Cat.No.	Product Name / Activity
2181	Vanilloid TRPV1 Receptor Tocriset™
	Selection of 5 vanilloid TRPV1 receptor ligands (Cat. Nos. 0462, 0934, 1137, 0464 and 1615)
Other
Cat.No.	Product Name / Activity
4104	MM-22
	Biotinylated anandamide analog; blocks anandamide uptake
2203	PALDA
	Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors
2204	STEARDA
	Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors
1684	Tocrisolve™ 100
	Water-soluble emulsion; negative control for reagents in Tocrisolve^TM 100