G Proteins (Heterotrimeric)

More Information »Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an α-, β- and γ-subunit and is bound to GDP in the 'off' state. Ligand binding causes a receptor conformational change, detaching the G protein and switching it 'on'.

G Protein (Heterotrimeric) Products

Product Name / Activity
2974 CCG 2046
Inhibitor of regulator of G-protein signaling 4 (RGS4)
4567 CCG 50014
Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein
4028 CCG 63802
Inhibitor of regulator of G-protein signaling 4 (RGS4) protein
4773 ESI 09
EPAC inhibitor
3090 Gallein
Inhibitor of βγ signaling
1931 G-Protein antagonist peptide
Inhibits G protein activation by GPCRs
3594 GRK2i
GRK2 inhibitory polypeptide. Gβγ antagonist
4742 Gue 1654
Selective inhibitor of OXE-R Gβγ signaling
1240 NF 023
Inhibitor of Go/i α-subunits; also P2X1 purinoceptor antagonist
1400 SCH 202676 hydrobromide
Inhibitor of ligand binding to G-protein-coupled receptors
1884 [D-Trp7,9,10]-Substance P
Inhibits M1 ACh receptor activation of Gq/11
Product Name / Activity
1192 Mastoparan
Activates Gi and Go
1896 Mastoparan X
G protein activator peptide
Product Name / Activity
1089 8-Bromo-cGMP, sodium salt
cGMP analog; activates PKG
1193 Melittin
Inhibits Gs and stimulates Gi activity
3097 Pertussis Toxin
Catalyzes ADP-ribosylation of Gi, Go and Gt
1472 Suramin hexasodium salt
Uncouples G proteins from receptors. Also purinoceptor antagonist
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