5-HT4 Receptors

More Information »Serotonin 5-HT4 receptors are located primarily in nigrostriatal and mesolimbic systems and smooth muscle. The receptor plays a role in memory and learning, anxiety, visual perception and smooth muscle relaxation.

5-HT4 Receptor Products

Agonists
Cat.No.
Product Name / Activity
4374 BIMU 8
Potent 5-HT4 receptor full agonist
1695 Cisapride
5-HT4 agonist; stimulates intestinal ACh release
3089 CJ 033466
Selective 5-HT4 partial agonist
3499 ML 10302 hydrochloride
Potent and selective 5-HT4 partial agonist
2844 Mosapride citrate
5-HT4 agonist and 5-HT3 antagonist
0736 2-[1-(4-Piperonyl)piperazinyl]benzothiazole
5-HT4 agonist. Also 5-HT3 antagonist
0989 RS 67333 hydrochloride
5-HT4 partial agonist
0990 RS 67506 hydrochloride
5-HT4 partial agonist
4613 Tegaserod maleate
5-HT4 partial agonist
1795 Zacopride hydrochloride
5-HT4 agonist. Also highly potent 5-HT3 antagonist
Antagonists
Cat.No.
Product Name / Activity
1322 GR 113808
Potent, selective 5-HT4 antagonist
1658 GR 125487 sulfamate
Potent, selective 5-HT4 antagonist; active in vivo
0728 RS 23597-190 hydrochloride
5-HT4 antagonist
0991 RS 39604 hydrochloride
5-HT4 antagonist
0785 SB 203186 hydrochloride
5-HT4 antagonist
1373 SB 204070
Potent and selective 5-HT4 antagonist
2037 SDZ 205-557 hydrochloride
5-HT4/5-HT3 receptor antagonist
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