R&D Systems Inc. Tocris Bioscience Boston Biochem

5-HT1D Receptors

More Information »Serotonin 5-HT1D receptors, previously known as 5-HT1Dα receptors, are located primarily in the basal ganglia, hippocampus, cortex, spinal cord and vascular smooth muscle cells. 5-HT1D receptors are thought to be involved in neuropsychiatric disorders such as depression.

5-HT1D Receptor Products

Product Name / Activity
3783 CP 135807
Selective 5-HT1D agonist
3665 Donitriptan hydrochloride
5-HT1B/1D agonist
3862 Eletriptan hydrobromide
Orally active, selective 5-HT1B/1D agonist
0864 GR 46611
5-HT1D agonist
0781 L-694,247
5-HT1D agonist
2640 L-703,664 succinate
Selective 5-HT1D receptor agonist
2556 PNU 109291
Potent and selective 5-HT1D agonist
1985 PNU 142633
Highly selective 5-HT1D agonist
5136 Rizatriptan benzoate
Potent 5-HT1B/1D agonist
3586 Sumatriptan succinate
5-HT1A/1B/1D receptor agonist
4657 Zolmitriptan
Potent 5-HT1B/1D/1F agonist
Product Name / Activity
1207 BRL 15572 hydrochloride
Selective h5-HT1D antagonist
1477 GR 127935 hydrochloride
Potent, selective 5-HT1B/1D antagonist
3078 LY 310762 hydrochloride
5-HT1D-preferring antagonist
3350 LY 393558
Dual 5-HT1B/1D antagonist and 5-HT re-uptake inhibitor
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Written by T. Kenakin et al

7-TM Poster

'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy

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Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

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