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5-HT_1D Receptors

More Information »Serotonin 5-HT_1D receptors, previously known as 5-HT_1Dα receptors, are located primarily in the basal ganglia, hippocampus, cortex, spinal cord and vascular smooth muscle cells. 5-HT_1D receptors are thought to be involved in neuropsychiatric disorders such as depression.

5-HT_1D Receptor Products

Agonists
Cat.No.	Product Name / Activity
3783	CP 135807
	Selective 5-HT1D agonist
3665	Donitriptan hydrochloride
	5-HT1B/1D agonist
3862	Eletriptan hydrobromide
	Orally active, selective 5-HT1B/1D agonist
0864	GR 46611
	5-HT1D agonist
0781	L-694,247
	5-HT1D agonist
2640	L-703,664 succinate
	Selective 5-HT1D receptor agonist
2556	PNU 109291
	Potent and selective 5-HT1D agonist
1985	PNU 142633
	Highly selective 5-HT1D agonist
3586	Sumatriptan
	5-HT1A/1B/1D receptor agonist
4657	Zolmitriptan
	Potent 5-HT1B/1D/1F agonist
Antagonists
Cat.No.	Product Name / Activity
1207	BRL 15572 hydrochloride
	Selective h5-HT1D antagonist
1477	GR 127935 hydrochloride
	Potent, selective 5-HT1B/1D antagonist
3078	LY 310762 hydrochloride
	5-HT1D-preferring antagonist
3350	LY 393558
	Dual 5-HT1B/1D antagonist and 5-HT re-uptake inhibitor

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