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NOP Receptors
More Information »The NOP receptor, (also known as ORL1, N/OFQ receptor), is a member of the opioid family of G-protein-coupled receptors that also includes κ, δ and μ receptors. The human gene encoding the NOP receptor has been localized to chromosome 20 (20q13.33).
NOP Receptor Products
Agonists |
|
Cat.No. |
Product Name / Activity |
| 3763 | MCOPPB trihydrochloride |
| Potent NOP receptor agonist | |
| 1780 | NNC 63-0532 |
| Potent non-peptide NOP agonist; brain penetrant | |
| 0910 | Nociceptin |
| Endogenous NOP agonist | |
| 1358 | Nociceptin (1-13)NH2 |
| Potent ORL1 agonist | |
| 1590 | [Arg14,Lys15]Nociceptin |
| Highly potent and selective NOP agonist | |
| 1566 | [(pF)Phe4]Nociceptin(1-13)NH2 |
| Potent, selective nociceptin receptor agonist | |
| 1092 | [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 |
| Selective nociceptin receptor agonist | |
| 3932 | Orphanin FQ (1-11) |
| Potent NOP agonist; displays analgesic properties | |
| 1387 | Ac-RYYRWK-NH2 |
| Potent, selective NOP partial agonist peptide | |
| 3240 | SCH 221510 |
| Potent and selective NOP agonist | |
Antagonists |
|
Cat.No. |
Product Name / Activity |
| 3661 | BAN ORL 24 |
| Potent and selective NOP antagonist | |
| 2598 | (±)-J 113397 |
| Potent and selective NOP antagonist | |
| 2481 | JTC 801 |
| Selective NOP antagonist | |
| 1308 | [Nphe1]Nociceptin(1-13)NH2 |
| Selective, competitive nociceptin antagonist | |
| 1118 | Nocistatin (bovine) |
| Opposes action of nociceptin | |
| 1198 | Nocistatin (human) |
| Human putative counterpart of nocistatin | |
| 3573 | SB 612111 hydrochloride |
| Selective NOP receptor antagonist | |
| 2508 | Trap 101 |
| Potent and selective NOP antagonist | |
| 1552 | UFP-101 |
| Potent, selective silent antagonist for NOP | |
Ligands |
|
Cat.No. |
Product Name / Activity |
| 1239 | Ac-RYYRIK-NH2 |
| High affinity NOP ligand | |
Other |
|
Cat.No. |
Product Name / Activity |
| 1266 | Nociceptin (1-7) |
| Bioactive metabolite of nociceptin | |
| 1119 | NocII |
| Orphan neuropeptide | |
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