D4 Receptors

More Information »D4 receptors are members of the dopamine receptor G-protein-coupled receptor family that also includes D1, D2, D3 and D5. They are located primarily in the frontal cortex, midbrain, amygdala and the cardiovascular system. A role in cognition and emotion has been proposed.

D4 Receptor Products

Product Name / Activity
4552 A 412997 dihydrochloride
Selective D4 agonist
2214 ABT 724 trihydrochloride
Potent, selective D4 partial agonist; proerectile
1065 PD 168077 maleate
High affinity, selective D4 agonist
2329 Ro 10-5824 dihydrochloride
Selective D4 receptor partial agonist
4380 WAY 100635 maleate
Dopamine D4 agonist. Also 5-HT1A silent antagonist
Product Name / Activity
2645 Fananserin
D4 antagonist. Also 5-HT2A antagonist
1004 L-741,742 hydrochloride
Highly selective D4 antagonist
1002 L-745,870 trihydrochloride
Highly selective D4 antagonist
3529 PD 168568 dihydrochloride
Potent and selective D4 antagonist
2735 PNU 96415E
D4 and 5-HT2A antagonist; antipsychotic
4185 Sonepiprazole
Selective D4 receptor antagonist
Product Name / Activity
3298 NGD 94-1
Selective D4 receptor ligand
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