R&D Systems Inc. Tocris Bioscience Boston Biochem

GABA Transporters

More Information »GABA transporters are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) that mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia.

GABA Products

Inhibitors
Cat.No.
Product Name / Activity
0206 β-Alanine
GABA uptake inhibitor (GAT-2 and -3). Also glycine receptor agonist
1296 CI 966 hydrochloride
Selective inhibitor of GAT-1
0234 Guvacine hydrochloride
Specific GABA uptake inhibitor
0236 (±)-Nipecotic acid
GABA uptake inhibitor
2747 NNC 05-2090 hydrochloride
GABA uptake inhibitor; moderately BGT-1 selective
1779 NNC 711
Selective inhibitor of GAT-1
0768 Riluzole hydrochloride
GABA uptake inhibitor. Also glutamate release inhibitor
1081 SKF 89976A hydrochloride
Potent GABA uptake inhibitor. Penetrates blood brain barrier
1561 (S)-SNAP 5114
GABA uptake inhibitor
0181 TACA
GABA uptake inhibitor. Also GABAA agonist and substrate for GABA-T
4256 Tiagabine hydrochloride
GABA uptake inhibitor; anticonvulsant

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GABA Review

GABA Receptors Review

Written by Ian Martin, Norman Bowery & Susan Dunn. Request a copy or view PDF today.

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Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Poster

'Schizophrenia - Emerging Targets and Therapeutic Strategies' provides a summary of the targets and pathways representing the most promising strategies to pursue for novel drug development.

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New Product Guide

NPG

Highlights over 130 new products added in the second half of 2013. Request a copy or view PDF today.

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Bio-Techne Events

British Society for Cardiovascular Research Autumn Meeting

British Society for Cardiovascular Research Autumn Meeting

September 8 - 9, 2014

Reading, UK