Adrenergic α₂ Receptors

More Information »Adrenergic α₂ receptors (α₂-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes α_1A, α_1B, α_1D, β₁, β₂ and β₃. Adrenergic α₂ receptors are divided into three subtypes in humans: α_2A, α_2B and α_2C.

Adrenergic α₂ Receptor Products

Agonists
Cat.No.	Product Name / Activity
2759	B-HT 920
	α₂ agonist. Also D₂ agonist and 5-HT₃ antagonist
2758	B-HT 933 dihydrochloride
	Selective α2 agonist
0690	Clonidine hydrochloride
	α₂ agonist. Also I₁ ligand
2749	Dexmedetomidine hydrochloride
	Potent, highly selective α₂ agonist. Active isomer of medetomidine (Cat. No. 2023)
0885	Guanabenz acetate
	α₂ agonist. Also I₂ selective ligand
1030	Guanfacine hydrochloride
	α_2A agonist
2023	Medetomidine hydrochloride
	Potent, highly selective α₂ agonist
2282	Moxonidine hydrochloride
	α₂ agonist. Also I₁ agonist
2948	(R)-(+)-m-Nitrobiphenyline oxalate
	Potent α_2C agonist
2242	Octopamine hydrochloride
	Invertebrate biogenic amine: activates α_2A and β₃ adrenoceptors
1142	Oxymetazoline hydrochloride
	α_2A partial agonist
0790	Rilmenidine hemifumarate
	α₂ agonist. Also I₁ ligand
3935	RWJ 52353
	α_2D agonist
2638	ST 91
	α₂ agonist, putative α_2C agonist
3609	Tizanidine hydrochloride
	α₂ agonist
0425	UK 14,304
	α₂ agonist
2466	UK 14,304 tartrate
	α₂ agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
Antagonists
Cat.No.	Product Name / Activity
2341	A 80426 mesylate
	High affinity α₂ antagonist. Also 5-HT uptake inhibitor
0928	ARC 239 dihydrochloride
	α_2B antagonist
2937	Atipamezole hydrochloride
	Selective α₂ antagonist
1133	BRL 44408 maleate
	Selective α_2A antagonist
0792	Efaroxan hydrochloride
	α₂ antagonist and I₁, I₃ ligand
0793	Idazoxan hydrochloride
	α₂ antagonist. Also I₂ ligand
0986	Imiloxan hydrochloride
	Highly selective α_2B antagonist
2666	JP 1302 dihydrochloride
	Potent and selective α_2C antagonist
2018	Mirtazapine
	α₂-antagonist. Also potent 5-HT₂, 5-HT₃ and H₁ antagonist. Antidepressant
0623	Prazosin hydrochloride
	α_2B and α₁ antagonist. MT₃ antagonist
0891	Rauwolscine hydrochloride
	α₂ antagonist
0987	RS 79948 hydrochloride
	Potent, selective α₂ antagonist
1324	RX 821002 hydrochloride
	Potent, selective α_2D antagonist
4508	S 32212 hydrochloride
	α₂ antagonist; 5-HT_2C inverse agonist
3866	SKF 86466 hydrochloride
	Potent and selective α₂ antagonist
0631	Spiroxatrine
	Potent α_2C antagonist
1127	Yohimbine hydrochloride
	Selective α₂ antagonist
Ligand Sets
Cat.No.	Product Name / Activity
1872	α₂-Adrenoceptor Tocriset™
	Selection of 5 α₂-adrenoceptor ligands (Cat. Nos. 1030, 0425, 0928, 1133 and 0891)
1875	Mixed Adrenergic Tocriset™
	Selection of 5 mixed adrenoceptor ligands (Cat. Nos. 0888, 0425, 1747, 0623 and 0952)
Ligands
Cat.No.	Product Name / Activity
0842	Agmatine sulfate
	α₂ ligand. Also imidazoline ligand

Related Categories

Adrenergic α₁ Receptors Adrenergic β₁ Receptors Adrenergic β₂ Receptors

Adrenergic Transporters Adrenergic β₃ Receptors

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