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Calcium-Activated Potassium (KCa) Channels
More Information »Calcium (Ca2+) -activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+ ions across biological membranes. They are broadly classified into three subtypes: SK, IK and BK channels (small, intermediate and big conductance).
Calcium-Activated Potassium (KCa) Channel Products
Activators |
|
Cat.No. |
Product Name / Activity |
| 2665 | BMS 191011 |
| Potent BKCa (KCa1.1) channel opener | |
| 2953 | CyPPA |
| Activator of KCa2.2 and KCa2.3 channels | |
| 1422 | DCEBIO |
| More potent analog of 1-EBIO (Cat. No. 1041). Activates hKCa3.1/Cl- conductance | |
| 1041 | 1-EBIO |
| Activator of epithelial KCa channels | |
| 4311 | GW 542573X |
| Selective activator of KCa2.1 channels | |
| 3804 | NS 1619 |
| Activator of BKCa (KCa1.1) channels | |
| 3895 | NS 309 |
| Positive modulator of KCa2 and KCa3.1 channels | |
| 3670 | SKA 31 |
| Activator of KCa3.1 and KCa2 channels | |
Blockers |
|
Cat.No. |
Product Name / Activity |
| 1652 | Apamin |
| KCa2 channel blocker (small conductance) | |
| 1087 | Charybdotoxin |
| KCa channel blocker (high conductance) | |
| 1086 | Iberiotoxin |
| KCa channel blocker (high conductance) | |
| 3564 | Kaliotoxin |
| KCa and KV blocker | |
| 4864 |
NS 6180
|
| Potent KCa3.1 channel blocker | |
| 2006 | Paxilline |
| Potent blocker of BKCa (KCa1.1) channels | |
| 4617 | Penitrem A |
| Potent and selective BKCa (KCa1.1) channel blocker | |
| 2946 | TRAM 34 |
| Highly selective KCa3.1 channel blocker | |
| 1310 | UCL 1684 |
| Highly potent blocker of KCa2 | |
| 2661 | UCL 2077 |
| Slow afterhyperpolarization (sAHP) channel blocker | |


