R&D Systems Inc. Tocris Bioscience Boston Biochem

LRRK2

More Information »Leucine-rich repeat kinase 2 (LRRK2), also known as dardarin, is a large multidomain protein kinase that includes leucine-rich repeats and a GTPase domain. Mutations in LRRK2 are commonly associated with late-onset Parkinson's disease (PD).

LRRK2 Products

Inhibitors
Cat.No.
Product Name / Activity
4534 CZC 54252 hydrochloride
Potent LRRK2 inhibitor; neuroprotective
4629 GSK2578215A
Potent, selective LRRK2 inhibitor; brain penetrant
4273 LRRK2-IN-1
Potent and selective LRRK2 inhibitor
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80 Kinase inhibitors
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Kinase Inhibitor Toolbox

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Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Poster

'Updated in 2014 - this poster summarizes the neurobiology of Parkinson's disease (PD), including new genetic insight, neurotransmitter pathways, and the role of aberrant α-synuclein metabolism in PD pathogenesis.

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New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.