R&D Systems Inc. Tocris Bioscience Boston Biochem

Hypoxia Inducible Factors

More Information »Hypoxia Inducible Factors (HIFs) are transcription factors that are activated in response to decreased oxygen availability in the cellular environment. They influence cell metabolism, cell survival and angiogenesis to maintain biological homeostasis.

Hypoxia Inducible Factor Products

Inhibitors
Cat.No.
Product Name / Activity
4408 DMOG
Prolylhydroxylase inhibitor
4451 IOX 2
Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
4324 KC7F2
HIF-1α inhibitor; down-regulates HIF-1α protein synthesis
2954 PX 12
Competitive thioredoxin-1 inhibitor
Activators
Cat.No.
Product Name / Activity
4565 ML 228
HIF pathway activator
Other
Cat.No.
Product Name / Activity
4705 Chetomin
Blocks interaction of HIF-1α, HIF-2α and STAT with CBP/p300

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Cancer Research Guide

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Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

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VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

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New Product Guide

NPG

Highlights over 130 new products added in 2012. Request a copy or view PDF today.

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Tocris Events

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Federation of European Biochemical Societies Congress 2013

Federation of European Biochemical Societies Congress 2013

July 6 - 11, 2013

St. Petersburg, Russia

Booth Number: 128