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Pregnane X Receptors
More Information »Pregnane X receptors (PXRs) are nuclear receptors that regulate the expression of CYP3A genes, generating key enzymes involved in xenobiotic metabolism. PXRs also help regulate the induction of P-gp. PXRs are highly expressed in the liver, small intestine and colon.
Pregnane X Receptor Products
Agonists |
|
Cat.No. |
Product Name / Activity |
| 4245 | Meclizine dihydrochloride |
| Human pregnane X receptor agonist; H1 antagonist | |
| 4121 | Rifampicin |
| Pregnane X receptor agonist; antibiotic | |
| 2969 | SR 12813 |
| Pregnane X receptor agonist | |





