Pregnane X Receptors
More Information »Pregnane X receptors (PXRs) are nuclear receptors that regulate the expression of CYP3A genes, generating key enzymes involved in xenobiotic metabolism. PXRs also help regulate the induction of P-gp. PXRs are highly expressed in the liver, small intestine and colon.
Pregnane X Receptor Products
Product Name / Activity
|Human pregnane X receptor agonist; H1 antagonist|
|Pregnane X receptor agonist; antibiotic|
|Pregnane X receptor agonist|
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Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.