Calcium-Sensing Receptor

More Information »The calcium-sensing receptor (CaSR) is a G-protein coupled receptor (GPCR) that senses extracellular Ca2+. The CaSR has wide tissue expression being found in the parathyroid gland, thyroid, kidney, intestine, skin, brain, heart, pancreas, bone and lung.

Calcium-Sensing Receptor Products

Product Name / Activity
4741 Gadolinium chloride
Stretch-activated calcium channel blocker; calcium-sensing receptor agonist
Product Name / Activity
3626 NPS 2143 hydrochloride
Selective antagonist of the calcium-sensing receptor; orally active calcilytic agent
Product Name / Activity
4387 Calhex 231 hydrochloride
Negative allosteric modulator of the calcium-sensing receptor
3815 R 568 hydrochloride
Positive allosteric modulator of the human calcium-sensing receptor
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