Calcium-Sensing Receptor

More Information »The calcium-sensing receptor (CaSR) is a G-protein coupled receptor (GPCR) that senses extracellular Ca²⁺. The CaSR has wide tissue expression being found in the parathyroid gland, thyroid, kidney, intestine, skin, brain, heart, pancreas, bone and lung.

Calcium-Sensing Receptor Products

Agonists
Cat.No.	Product Name / Activity
4741	Gadolinium chloride
	Stretch-activated calcium channel blocker; calcium-sensing receptor agonist
Antagonists
Cat.No.	Product Name / Activity
3626	NPS 2143 hydrochloride
	Selective antagonist of the calcium-sensing receptor; orally active calcilytic agent
Modulators
Cat.No.	Product Name / Activity
4387	Calhex 231 hydrochloride
	Negative allosteric modulator of the calcium-sensing receptor
3815	R 568 hydrochloride
	Positive allosteric modulator of the human calcium-sensing receptor