R&D Systems Inc. Tocris Bioscience Boston Biochem

Histone Methyltransferases

More Information »Histone methyltransferases (HMTs) are a group of enyzmes that catalyze the transfer of methyl groups from S-adenosylmethionine (SAM) to histones. This occurs predominantly on the side chains of lysine and arginine residues in histones H3 and H4.

Histone Methyltransferase Products

Inhibitors
Cat.No.
Product Name / Activity
5163 A 366
Potent and selective G9a/GLP histone lysine methyltransferase inhibitor
3364 BIX 01294
G9a-like protein and G9a histone lysine methyltransferase inhibitor
5128 C 21
Selective PRMT1 inhibitor
4504 Chaetocin
Histone methyltransferase SUV39H1 inhibitor
4703 3-Deazaneplanocin A hydrochloride
Histone methyltransferase inhibitor
5202 Furamidine dihydrochloride
Selective PRMT1 inhibitor
4892 (R)-PFI 2 hydrochloride
Potent and selective SETD7 histone lysine methyltransferase inhibitor
5400 (S)-PFI 2 hydrochloride
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
2609 Ryuvidine
Protein lysine methyltransferase SETD8 inhibitor; also CDK4 inhibitor
4541 SGC 0946
Highly potent and selective DOT1L inhibitor; cell permeable
5367 SGC 707
Potent and selective allosteric inhibitor of PRMT3
5099 TC-E 5003
Selective PRMT1 inhibitor
3861 UNC 0224
Potent G9a histone lysine methyltransferase inhibitor
4343 UNC 0638
Selective G9a and GLP histone lysine methyltransferase inhibitor
5132 UNC 0642
Potent and selective G9a and GLP histone lysine methyltransferase inhibitor
4342 UNC 0646
Potent and selective G9a/GLP inhibitor
4904 UNC 1999
Potent and selective EZH2/EZH1 histone lysine methyltransferase inhibitor
4905 UNC 2400
Negative control of UNC 1999 (Cat. No. 4904)
5450 XY1
Negative control of SGC 707 (Cat. No. 5367)
Other
Cat.No.
Product Name / Activity
5323 WDR5 0103
WDR5 antagonist
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