R&D Systems Inc. Tocris Bioscience Boston Biochem

Ca2+-ATPase

More Information »Ca2+-ATPases function to maintain a low cytoplasmic concentration of Ca2+ ions. They are high affinity, low capacitance transporters and complement the actions of the low affinity, high capacitance Na+/Ca2+ exchanger. Ca2+-ATPases are P-type ATPases.

Ca2+-ATPase Products

Inhibitors
Cat.No.
Product Name / Activity
2668 Artemisinin
Antimalarial; inhibits P-type ATPase (PfATP6) of P.falciparum
1236 BHQ
Inhibitor of SERCA ATPase
1235 Cyclopiazonic acid
Inhibitor of SERCA ATPase
1138 Thapsigargin
Potent inhibitor of SERCA ATPase
Activators
Cat.No.
Product Name / Activity
3807 Disulfiram
Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities
1291 Ochratoxin A
Stimulates SERCA-ATP-dependent Ca2+ pump activity
Blockers
Cat.No.
Product Name / Activity
2006 Paxilline
SERCA ATPase blocker. Also potent BKCa channel blocker
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Calcium Imbalance and Neuroprotective Targets

Written by E. Besancon et al

Neuroprotection Poster

'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.

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New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

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Bio-Techne Events

Pharmacology 2014

Pharmacology 2014

December 16 - 18, 2014

London, UK

Booth Number: 12