More Information »Gap channels (gap junctions) are specialized cell-cell contacts that provide direct intracellular communication. They allow passive diffusion of molecules up to 1 kDa, including nutrients, metabolites (glucose), ions (K+, Ca2+) and second messengers (IP3, cAMP).
Gap Channel Products
Product Name / Activity
|Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions|
|Scrambled version of 10Panx (Cat. No. 3348), Panx-1 mimetic inhibitory peptide|
|Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase|
|Gap junction blocker; inhibits smooth muscle contraction and IP3-mediated ATP release|
|Selective gap junction blocker|
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Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.