R&D Systems Inc. Tocris Bioscience Boston Biochem

Gap Channels

More Information »Gap channels (gap junctions) are specialized cell-cell contacts that provide direct intracellular communication. They allow passive diffusion of molecules up to 1 kDa, including nutrients, metabolites (glucose), ions (K+, Ca2+) and second messengers (IP3, cAMP).

Gap Channel Products

Inhibitors
Cat.No.
Product Name / Activity
3863 Trovafloxacin mesylate
Inhibits Panx-1; Antibiotic
Blockers
Cat.No.
Product Name / Activity
3348 10Panx
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
3708 Scrambled 10Panx
Scrambled version of 10Panx (Cat. No. 3348), Panx-1 mimetic inhibitory peptide
3096 Carbenoxolone disodium
Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
1950 Gap 26
Gap junction blocker; inhibits smooth muscle contraction and IP3-mediated ATP release
1476 Gap 27
Selective gap junction blocker
5353 Gap19
Cx43 hemichannel blocker

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Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

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Calcium Imbalance and Neuroprotective Targets

Written by E. Besancon et al

Neuroprotection Poster

'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.

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New Product Guide

NPG

Highlights 130 new products added in the first half of 2015. View PDF today.

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Bio-Techne Events

IBRO 2015

IBRO 2015

July 7 - 11, 2015

Rio de Janeiro, Brazil

Booth: B21