Gap Channels

More Information »Gap channels (gap junctions) are specialized cell-cell contacts that provide direct intracellular communication. They allow passive diffusion of molecules up to 1 kDa, including nutrients, metabolites (glucose), ions (K+, Ca2+) and second messengers (IP3, cAMP).

Gap Channel Products

Product Name / Activity
3863 Trovafloxacin mesylate
Inhibits Panx-1; Antibiotic
Product Name / Activity
3348 10Panx
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
3708 Scrambled 10Panx
Scrambled version of 10Panx (Cat. No. 3348), Panx-1 mimetic inhibitory peptide
3096 Carbenoxolone disodium
Gap junction blocker. Also inhibitor of 11 β-hydroxysteroid dehydrogenase
1950 Gap 26
Gap junction blocker; inhibits smooth muscle contraction and IP3-mediated ATP release
1476 Gap 27
Selective gap junction blocker
5353 Gap19
Cx43 hemichannel blocker

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