MEK

More Information »MEK (Mitogen-activated protein kinase kinase and MAP2K) is a kinase that phosphorylates mitogen activated protein kinases (MAPKs), ERK, p38 and JNK. There are seven MEK subtypes; MEK1 and 2 activate ERK, MEK3 and 4 activate p38 and MEK5 and 6 activate JNK.

MEK Products

Inhibitors
Cat.No.	Product Name / Activity
1777	Arctigenin
	Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
1532	10Z-Hymenialdisine
	Pan kinase inhibitor; potently inhibits MEK-1
4192	PD 0325901
	Selective inhibitor of MEK1/2
4237	PD 184352
	Selective MEK inhibitor
2605	PD 198306
	Potent inhibitor of MEK1/2
1213	PD 98059
	MEK inhibitor
1969	SL 327
	Selective inhibitor of MEK1 and MEK2; brain penetrant
1868	U0124
	Inactive analog of U0126 (Cat. No. 1144)
1144	U0126
	Potent, selective inhibitor of MEK1 and 2
Ligand Sets
Cat.No.	Product Name / Activity
2243	MEK Inhibitor Tocriset™
	Selection of 3 MEK inhibitors (Cat. Nos. 1213, 1969 and 1144)

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