More Information »Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes.

Cytokine Products

Product Name / Activity
2446 AS 101
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release
5430 AS 2444697
Potent and selective IRAK4 inhibitor
4316 Bropirimine
Immunomodulatory and antitumor compound
4204 BTZO 1
MIF binder
5484 C 87
TNF-α inhibitor
0846 Chicago Sky Blue 6B
MIF inhibitor; also inhibits L-glutamate uptake into synaptic vesicles
4400 (±)-CPSI 1306
Reported macrophage migration inhibitory factor (MIF) inhibitor
5479 CRID3 sodium salt
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
5601 DMXAA
mSTING agonist; induces antitumor immunological responses
2471 ER 27319 maleate
Inhibits TNF-α production
1798 Gabexate mesylate
Inhibits TNF-α production. Also antithrombotic agent
3270 GIT 27
Immunomodulator; reduces production of pro-inflammatory cytokines
1532 10Z-Hymenialdisine
Pan kinase inhibitor; blocks IL-8 production
5126 iMDK
Suppressor of MDK expression; inhibits PI 3-K signaling
3429 4-IPP
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
4288 ISO 1
Macrophage migration inhibitory factor (MIF) inhibitor
5185 JTE 607 dihydrochloride
Cytokine release inhibitor; anti-inflammatory
4656 (D)-(+)-Neopterin
Stimulated by IFN-γ; marker of immune activation
1093 Pirfenidone
Antifibrotic agent; regulates cytokine levels in vivo
4963 SC 144 hydrochloride
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
2008 SKF 86002 dihydrochloride
Inhibits human monocyte IL-1 and TNF-α production; p38 MAP kinase inhibitor
3543 Suplatast tosylate
Th2 cytokine synthesis inhibitor; antiasthmatic
0652 Thalidomide
TNF-α synthesis inhibitor
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