More Information »STATs (signal transducers and activators of transcription) are a family of seven transcription factors that form part of the JAK-STAT signaling cascade, the basis of the signal transduction mechanism for many cytokine receptors. STATs are activated by phosphorylation by JAKs.

STAT Products

Product Name / Activity
3713 Cryptotanshinone
STAT3 inhibitor. Also displays multiple other activities
1571 Cucurbitacin I
Selective inhibitor of STAT3/JAK2 signaling
5522 Napabucasin
Stat3 inhibitor; blocks cancer stem cell self-renewal
4079 Niclosamide
STAT3 inhibitor; also inhibits mTORC1 signaling
4655 NSC 74859
Selective STAT3 inhibitor
5138 RSVA 405
STAT3 inhibitor; also AMPK activator
3035 SD 1008
JAK2/STAT3 signaling pathway inhibitor
2798 Stattic
Selective STAT3 inhibitor
Product Name / Activity
3945 Colivelin
STAT3 activator. Also protects against β-amyloid neurotoxicity
Product Name / Activity
3495 Fludarabine
Purine analog; inhibits cytokine-induced STAT1 activation
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