G Proteins (Small)

More Information »Small G proteins (small GTPases) are homologous to G_α proteins and are often referred to as the Ras proto-oncogene superfamily. Small GTPases regulate a wide variety of processes in the cell, including growth, differentiation, movement and lipid vesicle transport.

G Protein (Small) Products

Inhibitors
Cat.No.	Product Name / Activity
3872	EHT 1864
	Potent inhibitor of Rac family GTPases
3584	Golgicide A
	Potent, specific and reversible inhibitor of GBF1 ArfGEF
3792	ITX 3
	Selective inhibitor of TrioN RhoGEF activity
4266	ML 141
	Selective inhibitor of Cdc42 Rho family GTPase
2161	NSC 23766
	Selective inhibitor of Rac1-GEF interaction; antioncogenic
3324	QS 11
	ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
2222	Rac1 Inhibitor F56, control peptide
	Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221	Rac1 Inhibitor W56
	Selective inhibitor of Rac1-GEF interaction
2849	SecinH3
	Sec7-specific GEF inhibitor (cytohesins)
3101	XRP44X
	Ras-Net pathway inhibitor
Activators
Cat.No.	Product Name / Activity
1089	8-Bromo-cGMP, sodium salt
	cGMP analog; activates PKG
1645	8CPT-2Me-cAMP, sodium salt
	Selective Epac activator
3715	Narciclasine
	Antiproliferative agent; stimulates RhoA activation
4853	8-pCPT-2-O-Me-cAMP-AM
	Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)