R&D Systems Inc. Tocris Bioscience Boston Biochem

G Proteins (Small)

More Information »Small G proteins (small GTPases) are homologous to Gα proteins and are often referred to as the Ras proto-oncogene superfamily. Small GTPases regulate a wide variety of processes in the cell, including growth, differentiation, movement and lipid vesicle transport.

G Protein (Small) Products

Inhibitors
Cat.No.
Product Name / Activity
5050 CASIN
Cdc42 GTPase inhibitor
3872 EHT 1864
Potent inhibitor of Rac family GTPases
3584 Golgicide A
Potent, specific and reversible inhibitor of GBF1 ArfGEF
4844 HJC 0350
Selective Epac2 inhibitor
3792 ITX 3
Selective inhibitor of TrioN RhoGEF activity
4266 ML 141
Selective inhibitor of Cdc42 Rho family GTPase
2161 NSC 23766
Selective inhibitor of Rac1-GEF interaction; antioncogenic
3324 QS 11
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
2222 Rac1 Inhibitor F56, control peptide
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221 Rac1 Inhibitor W56
Selective inhibitor of Rac1-GEF interaction
4989 Salirasib
Ras inhibitor; also induces autophagy
2849 SecinH3
Sec7-specific GEF inhibitor (cytohesins)
3101 XRP44X
Ras-Net pathway inhibitor
4794 ZCL 278
Cdc42 inhibitor
Activators
Cat.No.
Product Name / Activity
1089 8-Bromo-cGMP, sodium salt
cGMP analog; activates PKG
1645 8-CPT-2Me-cAMP, sodium salt
Selective Epac activator
3715 Narciclasine
Antiproliferative agent; stimulates RhoA activation
4853 8-pCPT-2-O-Me-cAMP-AM
Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
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