Matrix Metalloprotease

More Information »Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent endopeptidases and the major proteases in ECM degradation. MMPs are capable of degrading several extracellular molecules and a number of bioactive molecules.

Matrix Metalloprotease Products

Inhibitors
Cat.No.	Product Name / Activity
2621	ARP 100
	Selective inhibitor of MMP-2
2622	ARP 101
	Inhibitor of MMP-2
2961	Batimastat
	Potent, broad spectrum MMP inhibitor
2632	CL 82198 hydrochloride
	Selective inhibitor of MMP-13
3780	CP 471474
	Broad spectrum MMP inhibitor
4090	Doxycycline hyclate
	Broad-spectrum MMP inhibitor; tetracycline derivative
2631	Marimastat
	Broad spectrum MMP inhibitor
3268	Minocycline hydrochloride
	Inhibitor of MMP activity
2628	ONO 4817
	Broad spectrum MMP inhibitor
2520	PD 166793
	Broad spectrum MMP inhibitor
2916	Ro 32-3555
	Potent, collagenase-selective MMP inhibitor
4187	UK 356618
	Potent and selective MMP-3 inhibitor
2900	UK 370106
	Highly selective MMP-3 and MMP-12 inhibitor
4188	UK 383367
	Potent and selective BMP-1 (PCP) inhibitor
2633	WAY 170523
	Potent and selective inhibitor of MMP-13
Substrates
Cat.No.	Product Name / Activity
1892	Amyloid β-Peptide (10-20) (human)
	MMP-2/gelatinase A/type IV collagenase substrate
Other
Cat.No.	Product Name / Activity
3807	Disulfiram
	Inhibits expression of MMP-2 and MMP-9; displays a range of other activities