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Cyclin-Dependent Protein Kinase
More Information »Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the cyclins. Although there are 12 different cdk genes, only 5 have been shown to directly drive the cell cycle.
Cyclin-Dependent Protein Kinase Products
Inhibitors |
|
Cat.No. |
Product Name / Activity |
| 2072 | Aminopurvalanol A |
| Cyclin-dependent kinase inhibitor | |
| 2457 | Arcyriaflavin A |
| Potent cdk4/cyclin D1 and CaM Kinase II inhibitor. Antiviral agent (anti-HCMV) | |
| 3968 | AZD 5438 |
| Potent cyclin-dependent kinase (cdk) 1, 2 and 9 inhibitor | |
| 3605 | (R)-CR8 |
| Dual cdk1/cdk5 inhibitor. Also inhibits CK1 | |
| 3610 | (R)-DRF053 dihydrochloride |
| Dual cdk1/cdk5 inhibitor. Also inhibits CK1 | |
| 3094 |
Flavopiridol hydrochloride
|
| Cyclin-dependent kinase inhibitor | |
| 1813 | Indirubin-3'-oxime |
| Cyclin-dependent kinase inhibitor. Also inhibits other protein kinases | |
| 1398 | Kenpaullone |
| Potent cyclin-dependent kinase inhibitor. Also inhibits GSK-3 | |
| 2152 | NSC 625987 |
| Cyclin-dependent kinase 4 (cdk4) inhibitor | |
| 1867 | NSC 663284 |
| Cdc25 phosphatase inhibitor; blocks cdk1 and cdk2 activation | |
| 1937 | NSC 693868 |
| Cdk inhibitor. Also inhibits GSK-3 | |
| 3135 | NU 2058 |
| Cdk1 and cdk2 inhibitor | |
| 3301 | NU 6140 |
| Cyclin-dependent kinase 2 (cdk2) inhibitor | |
| 1284 | Olomoucine |
| Cyclin-dependent kinase inhibitor | |
| 1902 | [Ala92]-p16 (84-103) |
| Cyclin-dependent kinase inhibitor | |
| 4786 |
PD 0332991 isethionate
|
| Potent, selective Cdk4/6 inhibitor; brain penetrant | |
| 3140 | PHA 767491 hydrochloride |
| Dual cdc7/cdk9 inhibitor. Also inhibits MK2 | |
| 1580 | Purvalanol A |
| Cyclin-dependent kinase inhibitor | |
| 1581 | Purvalanol B |
| Cyclin-dependent kinase inhibitor | |
| 4181 | Ro 3306 |
| Cyclin-dependent kinase (cdk) 1 inhibitor | |
| 2609 | Ryuvidine |
| Cyclin-dependent kinase 4 (cdk4) inhibitor | |
| 4075 | SNS 032 |
| Potent cdk2, cdk7 and cdk9 inhibitor | |
| 2907 | SU 9516 |
| Potent cdk2 inhibitor | |
Blockers |
|
Cat.No. |
Product Name / Activity |
| 1532 |
10Z-Hymenialdisine
|
| Pan kinase inhibitor; potently inhibits Cdk1, Cdk2, Cdk3 and Cdk5 | |
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Cancer Research Guide
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Kinases Product Listing
Highlights over 350 products for kinase research. Request a copy or view PDF today.
Kinase Inhibitor Toolbox
80 Kinase inhibitors
pre-dissolved in DMSO
Some of the most potent
kinase inhibitors all on one plate
Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.
Checkpoint Kinases & the DNA Damage Response
Written by Michelle D. Garrett and Ian Collins
A summary of the response of the checkpoint kinase signaling network to DNA damage, including activation of DNA repair, cell-cycle arrest, senescence and apoptosis.
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