Inhibitor of Apoptosis

More Information »The inhibitor of apoptosis (IAP) family of proteins are major regulators of apoptosis through interaction with components of the apoptotic signaling cascades. Discovered in baculovirus, human homologs can be described as baculovirus IAP repeat containing (BIRC) proteins.

Inhibitor of Apoptosis Products

Product Name / Activity
5141 AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
2156 Embelin
Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor
5251 UC 112
IAP and XIAP inhibitor; antitumor
Product Name / Activity
3253 Triptolide
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
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Programmed Cell Death

Written by Bram van Raam and Guy Salvesen

Programmed Cell Death Life Science Poster

A summary of the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation. Request copy or view PDF today.

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