R&D Systems Inc. Tocris Bioscience Boston Biochem

Apoptosis

Apoptosis is defined as a mechanism of cell death which occurs after sufficient cellular damage. It occurs normally during development and aging and is considered a vital component of cell turnover, cell development and function of the immune system. It occurs as a defense mechanism such as in immune reactions or when cells are damaged by disease or noxious agents.

Products for Apoptosis

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Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.

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Apoptosis and Disease

Apoptosis, in general, confers advantages during an organism's life cycle. Between 50 billion and 70 billion cells die each day due to apoptosis in the average human adult. In a year, this amounts to the proliferation and subsequent destruction of a mass of cells equal to an individual's body weight. Inappropriate apoptosis is a factor in many human conditions including neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of cancer. The ability to modulate the life or death of a cell is recognized for its profound therapeutic potential, and research continues to focus on the elucidation of the cell cycle machinery and signaling pathways that control cell cycle arrest and apoptosis.

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Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

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Checkpoint Kinases & the DNA Damage Response

Written by Michelle D. Garrett and Ian Collins

Cell Cycle Kinases Poster

A summary of the response of the checkpoint kinase signaling network to DNA damage, including activation of DNA repair, cell-cycle arrest, senescence and apoptosis.

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Programmed Cell Death

Written by Bram van Raam and Guy Salvesen

Programmed Cell Death Poster

A summary of the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation. Request a copy or view PDF today.

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New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

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Bio-Techne Events

FEBS-EMBO 2014 Meeting

FEBS-EMBO 2014

August 30 - September 4, 2014

Paris, France

Booth Number: 22