R&D Systems Inc. Tocris Bioscience Boston Biochem

Insulin and Insulin-like Receptors

More Information »Insulin receptors (IRs) and insulin-like growth factor receptors (IGFRs) are formed from two subunits, each of which is comprised of an extracellular α-subunit and a transmembrane β-subunit with intracellular tyrosine kinase activity. IR homodimers are activated by insulin.

Insulin and Insulin-like Receptor Products

Inhibitors
Cat.No.
Product Name / Activity
4774 BMS 536924
Dual IR/IGF1R inhibitor
5111 GSK 1838705
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
5247 NVP ADW 742
ATP-competitive inhibitor of IGF1R
2956 Picropodophyllotoxin
Selective IGF1R inhibitor
2768 PQ 401
IGF1R inhibitor
Activators
Cat.No.
Product Name / Activity
1819 Demethylasterriquinone B1
Selective insulin RTK activator
3435 Insulin (human) recombinant
expressed in yeast
Endogenous peptide agonist
Other
Cat.No.
Product Name / Activity
5154 HNGF6A
Humanin analog; increases insulin sensitivity
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Kinases Product Listing

Kinases Product Listing

Highlights over 350 products for kinase research. Request a copy or view PDF today.

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Kinase Inhibitor Toolbox

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Appetite Modulation

Peptides Involved in Appetite Modulation Review

Written by Sonia A. Tucci, Lynsay Kobelis & Tim Kirkham. Request a copy or view PDF today.

divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

divider line

Gut Hormones and the Regulation of Appetite

Written by V.J. Taylor et al

Gut Hormones Poster

'Gut Hormones and the Regulation of Appetite' summarizes the neuropeptide modulators and gut hormones that influence appetite

divider line

New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

divider line

Bio-Techne Events

Pharmacology 2014

Pharmacology 2014

December 16 - 18, 2014

London, UK

Booth Number: 12