Insulin and Insulin-like Receptors

More Information »Insulin receptors (IRs) and insulin-like growth factor receptors (IGFRs) are formed from two subunits, each of which is comprised of an extracellular α-subunit and a transmembrane β-subunit with intracellular tyrosine kinase activity. IR homodimers are activated by insulin.

Insulin and Insulin-like Receptor Products

Product Name / Activity
4774 BMS 536924
Dual IR/IGF1R inhibitor
5111 GSK 1838705
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
5247 NVP ADW 742
ATP-competitive inhibitor of IGF1R
2956 Picropodophyllotoxin
Selective IGF1R inhibitor
2768 PQ 401
IGF1R inhibitor
Product Name / Activity
1819 Demethylasterriquinone B1
Selective insulin RTK activator
3435 Insulin (human) recombinant
expressed in yeast
Endogenous peptide agonist
Product Name / Activity
5402 6bK
Insulin degrading enzyme (IDE) inhibitor
5154 HNGF6A
Humanin analog; increases insulin sensitivity
5192 NBI 31772
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Kinase Inhibitor Toolbox

80 Kinase inhibitors
pre-dissolved in DMSO

Kinase Inhibitor Toolbox

Includes many of the latest kinase inhibitors to become commercially available. Covers a wide range of kinase targets including EGFR, MAPK and CDK.

divider line

Kinases Product Listing

Kinases Product Listing

Highlights over 400 products for kinase research. Request copy or view PDF today.

divider line

Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia A. Tucci, Lynsay Kobelis & Tim Kirkham. View PDF today.

divider line

VEGF Pathway & Anti-Angiogenic Therapy

Written by N. Ferrara & Y. Crawford

Angiogenesis Life Science Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance. Request copy today.

divider line

Gut Hormones and the Regulation of Appetite

Written by V.J. Taylor et al

Gut Hormones Life Science Poster

'Gut Hormones and the Regulation of Appetite' summaries the neuropeptide modulators and gut hormones that influence appetite. Request copy today.

divider line

Insulin Pathway

Insulin Signaling Pathway

Signals through the insulin pathway are fundamental for the regulation of intracellular glucose levels. View pathway or download PDF today.

divider line

AAI 2016

Win a $1,000 travel grant

AAI Travel Grant

Bio-Techne is offering 10 travel grants of $1,000 for AAI 2016.