MET Receptor

More Information »The MET receptor, also known as hepatocyte growth factor receptor (HGFR), is a proto-oncogenic receptor tyrosine kinase. The endogenous ligand for MET is hepatocyte growth factor/scatter factor (HGF), a disulfide-linked heterodimeric molecule.

MET Receptor Products

Product Name / Activity
4368 Crizotinib
Potent c-MET/ALK inhibitor
1683 K 252a
Receptor tyrosine kinase inhibitor, inhibits MET
5369 Norleual
Highly potent HGF/c-MET inhibitor; also AT4 antagonist
4239 PF 04217903 mesylate
Highly selective c-Met inhibitor
2693 PHA 665752
Potent and selective MET inhibitor
5356 SGX 523
Selective and potent c-MET kinase inhibitor
4101 SU 11274
Selective inhibitor of MET kinase activity
3037 SU 5416
MET inhibitor. Also inhibits KIT, RET, VEGFR and FLT3
5422 XL 184
Potent c-MET inhibitor; also inhibits other RTKs
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Written by N. Ferrara & Y. Crawford

Angiogenesis Poster

A summary of antiangiogenic therapies targeting the VEGF pathway and the mechanisms of therapy resistance.

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New Product Guide


Highlights 130 new products added in the first half of 2015. View PDF today.

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