More Information »γ-secretase is a multi-subunit internal protease that cleaves within the transmembrane domain of its substrates. It is an integral membrane protein and minimally consists of four proteins; presenilin, nicastrin, APH-1 and PEN-2. γ-secretase is involved in the processing of Notch.
Product Name / Activity
|γ-secretase inhibitor; lowers Aβ40 and Aβ42 levels|
|Potent γ-secretase inhibitor|
|γ-secretase inhibitor; inhibits Notch pathway|
|γ-secretase inhibitor; lowers Aβ42 levels in vitro|
|Inhibitor of γ-secretase-mediated βAPP processing|
|Potent and selective γ-secretase inhibitor|
|γ-secretase inhibitor; attenuates amyloid plaque deposition|
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