R&D Systems Inc. Tocris Bioscience Boston Biochem

Matrix Metalloprotease

More Information »Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent endopeptidases and the major proteases in ECM degradation. MMPs are capable of degrading several extracellular molecules and a number of bioactive molecules.

Matrix Metalloprotease Products

Inhibitors
Cat.No.
Product Name / Activity
2621 ARP 100
Selective inhibitor of MMP-2
2622 ARP 101
Inhibitor of MMP-2
2961 Batimastat
Potent, broad spectrum MMP inhibitor
2632 CL 82198 hydrochloride
Selective inhibitor of MMP-13
3780 CP 471474
Broad spectrum MMP inhibitor
4090 Doxycycline hyclate
Broad-spectrum MMP inhibitor; tetracycline derivative
3995 GI 254023X
Selective ADAM10 metalloprotease inhibitor
2983 GM 6001
Broad spectrum MMP inhibitor
2631 Marimastat
Broad spectrum MMP inhibitor
3268 Minocycline hydrochloride
Inhibitor of MMP activity
4902 NSC 405020
Inhibitor of MT1-MMP; antitumor
2628 ONO 4817
Broad spectrum MMP inhibitor
2520 PD 166793
Broad spectrum MMP inhibitor
2916 Ro 32-3555
Potent, collagenase-selective MMP inhibitor
4187 UK 356618
Potent and selective MMP-3 inhibitor
2900 UK 370106
Highly selective MMP-3 and MMP-12 inhibitor
4188 UK 383367
Potent and selective BMP-1 (PCP) inhibitor
2633 WAY 170523
Potent and selective inhibitor of MMP-13
Substrates
Cat.No.
Product Name / Activity
1892 Amyloid β-Peptide (10-20) (human)
MMP-2/gelatinase A/type IV collagenase substrate
Other
Cat.No.
Product Name / Activity
3807 Disulfiram
Inhibits expression of MMP-2 and MMP-9; displays a range of other activities
4604 PTIQ
Potent MMP-3 expression inhibitor; neuroprotective
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