More Information »IκB Kinase (IKK) is an enzyme complex that forms part of the NF-κB signaling pathway. The IKK complex is comprised of three subunits (IKKα (IKK1), IKKβ (IKK2) and IKKγ (NEMO)), the α- and β-subunits are catalytically active whereas the γ-subunit has a regulatory function.
IκB Kinase Products
Product Name / Activity
|Selective IKKα and IKKβ inhibitor|
|Inhibitor of TBK1 and IKKε; antiallergic agent|
|Selective inhibitor of IKK|
|Inhibitor of IKKβ|
|Potent and selective IKKβ inhibitor|
|IKKβ inhibitor; attenuates NF-κB-induced gene expression|
|Potent, selective inhibitor of IKKβ|
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Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.