IκB Kinase

More Information »IκB Kinase (IKK) is an enzyme complex that forms part of the NF-κB signaling pathway. The IKK complex is comprised of three subunits (IKKα (IKK1), IKKβ (IKK2) and IKKγ (NEMO)), the α- and β-subunits are catalytically active whereas the γ-subunit has a regulatory function.

IκB Kinase Products

Inhibitors
Cat.No.
Product Name / Activity
4547 ACHP
Selective IKKα and IKKβ inhibitor
4857 Amlexanox
Inhibitor of TBK1 and IKKε; antiallergic agent
4806 BMS 345541
Selective allosteric inhibitor of IKK; anti-inflammatory
2539 IKK 16
Selective inhibitor of IKK
2611 IMD 0354
Inhibitor of IKKβ
4899 ML 120B dihydrochloride
Novel IKK2-selective inhibitor
4238 PF 184
Potent and selective IKKβ inhibitor
4569 PS 1145 dihydrochloride
Selective IKK inhibitor; orally active
3318 SC 514
IKKβ inhibitor; attenuates NF-κB-induced gene expression
2559 TPCA-1
Potent, selective inhibitor of IKKβ
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