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KISS-Derived Peptide (KISS1) Receptors
More Information »The KISS-derived peptide receptor (KISS1) is a Gq/G11-protein-coupled receptor that signals through stimulation of phospholipase C resulting in Ca2+ mobilization. The KISS-derived peptide receptor plays a key role in the neuroendocrine control of the gonadotrophin axis.
KISS-Derived Peptide (KISS1) Receptor Products
Agonists |
|
Cat.No. |
Product Name / Activity |
| 2570 | Kisspeptin 10 (human) |
| Endogenous ligand for KISS1 receptor (hOT7T175/AXOR12/GPR54) | |
| 4243 | Kisspeptin 10 (rat) |
| Endogenous ligand for KISS1 receptor | |
| 1443 | Metastin (human) |
| Potent, endogenous ligand for KISS1 receptor (hOT7T175/AXOR12/GPR54) | |
Antagonists |
|
Cat.No. |
Product Name / Activity |
| 3881 | Kisspeptin 234 |
| KISS1/GPR54 antagonist; kisspeptin 10 (Cat. No. 2570) analog | |
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7-TM Receptor Signaling
Written by T. Kenakin et al
'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy
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Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.