R&D Systems Inc. Tocris Bioscience Boston Biochem

Protein Kinase C

More Information »Protein kinase C (PKC) refers to a family of serine/threonine protein kinases grouped by their activation mechanism. Conventional PKCs (cPKC α-, βI- , βII- and γ-) are activated by phosphatidylserine in a calcium dependent manner and can bind diacylglycerol.

Protein Kinase C Products

Inhibitors
Cat.No.
Product Name / Activity
4128 Bisindolylmaleimide II
Potent PKC inhibitor and nicotinic receptor antagonist
0543 C-1
Protein kinase C inhibitor
1626 Calphostin C
Potent, selective and photo-dependent PKC inhibitor
2442 CGP 53353
Selective inhibitor of PKCβII
1330 Chelerythrine chloride
Cell-permeable protein kinase C inhibitor
0749 Dihydrosphingosine
Protein kinase C inhibitor
0741 GF 109203X
Protein kinase C inhibitor
2253 Go 6976
Potent protein kinase C inhibitor; selective for α and β isozymes
2285 Go 6983
Broad spectrum PKC inhibitor
2287 K-252c
Protein kinase C inhibitor
4738 LY 333531 hydrochloride
Protein kinase C inhibitor; selective for β isozymes
1900 [Ala107]-MBP (104-118)
Protein kinase C inhibitor
1901 [Ala113]-MBP (104-118)
Protein kinase C inhibitor
1193 Melittin
Inhibits protein kinase C and cAMP-dependent protein kinase
0609 (±)-Palmitoylcarnitine chloride
Protein kinase C inhibitor
4058 PKC (19-36)
Pseudosubstrate peptide; inhibitor of PKC
4059 [Glu27]-PKC (19-36)
Inactive control peptide for PKC (19-36) (Cat. No. 4058)
2992 PKC 412
Protein kinase C inhibitor
1792 PKC β pseudosubstrate
Selective cell-permeable PKC inhibitor peptide (attached to vector)
1791 PKC ζ pseudosubstrate
PKC ζ inhibitor peptide (attached to cell-permeable vector)
1587 Ro 32-0432 hydrochloride
Potent, orally active PKC inhibitor
1610 Rottlerin
Reported PKCδ inhibitor
0633 D-erythro-Sphingosine (synthetic)
Protein kinase C inhibitor
4221 TCS 21311
PKCα and PKCθ inhibitor. Also inhibits JAK3
2549 ZIP
Cell-permeable inhibitor of atypical PKC isozyme PKMζ
3215 ZIP (Scrambled)
Control peptide for ZIP (Cat. No. 2549)
3290 ZIP, Biotinylated
Biotinylated peptide for ZIP (Cat. No. 2549)
Activators
Cat.No.
Product Name / Activity
2383 Bryostatin 1
Protein kinase C activator
3091 FR 236924
Selective PKCε activator
3651 (-)-Indolactam V
Protein kinase C activator
4054 PEP 005
Protein kinase C activator
4153 Phorbol 12,13-dibutyrate
Protein kinase C activator
1201 Phorbol 12-myristate 13-acetate
Protein kinase C activator
1887 PKC fragment (530-558)
Potent activator of protein kinase C
1790 Pseudo RACK1
Protein kinase C activator peptide (attached to cell permeable vector)
0430 SC-10
Protein kinase C activator
0433 SC-9
Protein kinase C activator
Other
Cat.No.
Product Name / Activity
3427 Oncrasin 1
Induces abnormal nuclear aggregation of PKCι; proapoptotic

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