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Akt (Protein Kinase B)
More Information »Akt (Protein kinase B, PKB) is a serine/threonine kinase that plays a key in regulating cell survival, insulin signaling, angiogenesis and tumor formation. Akt is a downstream mediator of the PI 3-K pathway, which results in the recruitment of Akt to the plasma membrane.
Akt (Protein Kinase B) Products
Inhibitors |
|
Cat.No. |
Product Name / Activity |
| 3897 | API-1 |
| Selective Akt/PKB inhibitor. Antitumor | |
| 2151 | API-2 |
| Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral | |
| 2558 | 10-DEBC hydrochloride |
| Selective Akt/PKB inhibitor | |
| 2926 | FPA 124 |
| Akt/PKB inhibitor | |
| 4144 | GSK 690693 |
| Akt kinase inhibitor. Antitumor | |
| 4398 | SC 66 |
| Allosteric Akt inhibitor | |
Substrates |
|
Cat.No. |
Product Name / Activity |
| 1353 | Akt/SKG Substrate Peptide |
| Akt/PKB substrate (synthetic) | |
| 2422 | AKTide-2T |
| Akt/PKB substrate (synthetic) | |
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Akt Pathway
Akt signaling is involved in fundamental cellular processes such as protein synthesis, metabolism, proliferation and survival. View pathway or download PDF today.
20% Discount*
Potent, selective LRRK2 inhibitor
Tocris is the first to launch GSK2578215A, licensed from GlaxoSmithKline, for the study of Parkinson's Disease.