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Apelin Receptor
More Information »Apelin-36, apelin-13 and [Pyr1]-apelin-13 are the predominant endogenous ligands for the apelin receptor (APJ) receptor. The APJ receptor and apelin peptides act as mediators of cardiovascular function, fluid homeostasis and adipocyte endocrine secretion.
Apelin Receptor Products
Agonists |
|
Cat.No. |
Product Name / Activity |
| 2420 | [Pyr1]-Apelin-13 |
| Potent peptide agonist for APJ receptor | |
| 3007 | Apelin-17 (human, bovine) |
| Endogenous APJ receptor agonist | |
| 2426 | Apelin-36 (human) |
| Endogenous APJ receptor agonist | |
| 2427 | Apelin-36 (rat, mouse) |
| Endogenous APJ receptor agonist | |
Antagonists |
|
Cat.No. |
Product Name / Activity |
| 4748 |
ML 221
|
| Apelin receptor (APJ) antagonist | |
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7-TM Receptor Signaling
Written by T. Kenakin et al
'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy
Regulation of Vascular Reactivity by GPCRs
Written by J.J. Maguire and A.P. Davenport
'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity.
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