All Products

Cat.No.

Product Name / Activity

FH2 domain inhibitor; prevents actin nucleation

Ligand of GPR103; orexigenic neuropeptide

Histone deacetylase inhibitor

Positive allosteric modulator of M₅ receptors

Potent EphB4 kinase inhibitor

Prolylhydroxylase inhibitor

High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation

GABA_A modulator; anxiolytic

Non-selective serotonin receptor agonist

Functionally selective GABA_A receptor (α3 subtype) partial agonist

Subtype-selective GABA_A receptor partial agonist

Negative allosteric modulator at mGlu₅

Selective and reversible p97 inhibitor

HIV protease inhibitor

Antibiotic; neutralizes LPS

Analog of LF 11 (Cat. No. 4421); antibiotic

Highly selective GSK-3 inhibitor

Selective α3β4 nAChR antagonist

Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties

Xanthine oxidase inhibitor

Fluorescent mitochondrial hydrogen peroxide indicator

Inhibitor of apoptosis signal-regulating kinase 1 (ASK1)

Soluble guanylyl cyclase (sGC) activator

Highly potent, selective GSK-3 inhibitor

High affinity, selective CK2 inhibitor

Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal

N-WASP inhibitor; inhibits Arp2/3 activation

Selective Na_V1.7 blocker

Cytotoxic nucleoside analog; inhibits RNA synthesis

Positive allosteric modulator of mGlu₅

Negative allosteric modulator at mGlu₅

Neurogenic agent; induces NeuroD1 expression

Dual AChE and BChE inhibitor

α7 nAChR agonist; histamine H₃ antagonist

Inhibits synaptosomal dopamine and 5-HT uptake

Cell permeable inhibitor of SREBP activation

BET bromodomain inhibitor

Krüppel-like factor 5 (KLF5) inhibitor

Ceramidase inhibitor; antiproliferative

Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

Potent B-Raf inhibitor

Cyclooxygenase inhibitor; NSAID

ACE inhibitor; also inhibits LTA₄ hydrolase

5-HT and noradrenalin re-uptake inhibitor

GPR35 agonist

Potent mGlu₅ allosteric potentiator

Thymidylate synthase inhibitor; induces DNA fragmentation

K_V11.1 (hERG) channel activator. Antiarrhythmic

REV-ERBα antagonist

Histone demethylase inhibitor; cell permeable

Potent and selective ERK2 inhibitor

Potent GABA_A antagonist

Long-acting 5-HT_2A antagonist

Positive allosteric modulator at mGlu₄

Selective 5-HT_2A antagonist

Selective VEGFR-2 inhibitor

Potent A_2B receptor agonist; cardioprotective

Potent and selective P2X₇ antagonist

Allosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation

Inhibitor of Wnt/β-catenin signaling

Selective α7 nAChR agonist

Inhibits IRE1α endoribonuclease activity

Selective 5-HT_2A antagonist; antithrombotic

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

CaM kinase III (eEF-2 kinase) inhibitor

GLUT1 inhibitor

USP7 inhibitor

Non-selective protease inhibitor; also blocks anandamide metabolism

Adenosine deaminase inhibitor

γ-secretease inhibitor; inhibits Notch pathway

Antiproliferative; induces activin/SMAD3 signaling

Selective NR2C/NR2D receptor antagonist

Atypical antipsychotic; 5-HT_2A and D₂ antagonist

Enantiomer of DPN (Cat. No. 1494)

γ-secretase inhibitor; lowers Aβ42 levels in vitro

Selective PDE11 inhibitor

Potent and selective FAK inhibitor

Potent, selective BET bromodomain inhibitor; cell permeable