All Products

Cat.No.

Product Name / Activity

CXCR4 antagonist; CXCR7 agonist

Potent and selective inhibitor of DAPK1

Angiotensin-converting enzyme (ACE) inhibitor

K_V7.2/K_V7.3 channel opener

Selective CCR2 antagonist

Soluble guanylyl cyclase (sGC) activator; induces G₁ cell cycle arrest

Selective, irreversible MAO-B inhibitor

Cell-permeable Zn²⁺ chelator

Selective inhibitor of myosin light chain kinase

Selective activator of K_Ca2.1 channels

Selective K⁺ ionophore

Selective non-peptide CGRP₁ antagonist

Immunomodulatory and antitumor compound

Selective OX₂ receptor antagonist

PDK1 inhibitor

Potent and selective TRPV1 antagonist

CXCR4 antagonist

Positive allosteric modulator at mGlu₅

HIF-1α inhibitor; down-regulates HIF-1α protein synthesis

Phosphate reservoir

p53 stabilizing agent

Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)

Potent, selective P2Y₂ agonist

Low-internalizing δ opioid receptor agonist

Potent, ATP-competitive inhibitor of Clk-family kinases

Selective, high affinity 5-HT₆ agonist

JAK2 inhibitor

Selective K_ir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)

Partial agonist at α7 nAChR

Potent and selective G9a/GLP inhibitor

Selective G9a and GLP histone lysine methyltransferase inhibitor

Inhibitor of Wnt/β-catenin signaling

Potent, high affinity CB₁ receptor inverse agonist

Positive allosteric modulator of mGlu₁

Positive allosteric modulator of group I mGlu receptors

Positive allosteric modulator of mGlu₁

5-HT_2A/D₂ antagonist; atypical antipsychotic

Potent VEGFR-1, -2 and -3 inhibitor

High affinity dopamine uptake inhibitor

Selective inhibitor of noradrenalin transporters

Potent and selective GSK-3β inhibitor

Inhibits NOD1-induced NF-κB activation

Potent, reversible and selective FAAH inhibitor

Noradrenalin, 5-HT and dopamine re-uptake inhibitor

Selective serotonin reuptake inhibitor

MGMT inhibitor

Dual Src-Abl inhibitor; antiproliferative

Potent LpxC inhibitor

Potent S1P₁ receptor agonist

Selective melanin-concentrating hormone receptor 1 (MCH₁R) antagonist

Potent K_V1.3 channel blocker

Potent c-MET/ALK inhibitor

Potent, selective mGlu₄ positive allosteric modulator

Positive allosteric modulator at mGlu₄

Selective urokinase (uPA) inhibitor

Positive allosteric modulator of GluA2 receptors

Potent 5-HT₄ receptor full agonist

Specific inhibitor of E3 ubiquitin ligase

Potent P2Y₆ agonist

Selective liver receptor homolog-1 (LRH-1) agonist

NMDA receptor antagonist; enantiomer of ketamine hydrochloride (Cat. No. 3131)

Potent, 5-HT_1A silent antagonist. Also D₄ agonist

Negative allosteric modulator at mGlu₅

Potent, reversible non-steroidal aromatase inhibitor

Potent AChE inhibitor

Selective P2X₃, P2X_2/3 antagonist

Negative allosteric modulator of the calcium-sensing receptor

Selective negative allosteric modulator of group II mGlu receptors

Potent O-GlcNAcase inhibitor

Potent P2X₃, P2X_2/3 antagonist

Potent and selective inhibitor of tryptophan 2,3-dioxygenase

Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand

Negative allosteric modulator at mGlu₅

Reversible MAO-A inhibitor

Induces apoptosis; increases p53 and ROS levels in cancer cells

Allosteric Akt inhibitor

Selective allosteric inhibitor of Bcr-abl tyrosine kinase activity