All Products

Cat.No.

Product Name / Activity

Antibody recognizing p14^ARF

Antibody recognizing p53

Antibody recognizing p53

Antibody recognizing p53

Antibody recognizing p53

Antibody recognizing PARP2

Antibody recognizing PIP₂

Antibody recognizing PKCα

Antibody recognizing PLK4

Antibody recognizing PPARδ

Potent K_ATP channel opener

Cyclin-dependent kinase inhibitor

Selection of 3 p38 MAPK inhibitors (Cat. Nos. 1264, 1202 and 1962)

Antagonist of neurosteroid potentiation and direct gating of GABA_A

Activator of procaspase-3; pro-apoptotic

Potent stimulator of adenylyl cyclase

Potent stimulator of adenylyl cyclase

Potent PAC₁ receptor antagonist

Phospholipase A₂ inhibitor

Endogenous platelet-activating factor (PAF)

Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors

Protein kinase C inhibitor

Selective GPR55 agonist. FAAH and PAA substrate

Endogenous lipid; enhances activity of 2-AG

Inhibitor of FAAH

NPY Y₄ agonist; involved in gastrointestinal tract function

Potent, selective neuropeptide Y Y₅ agonist

Nicotinic (neuromuscular) antagonist

PAR₄ peptide fragment; acts as a PAR₄ agonist

Parathyroid hormone (PTH) receptor agonist

Highly potent and selective 5-HT uptake inhibitor

Peptide cleaved from PAR₁ upon receptor activation

Peptide cleaved from PAR₁ upon receptor activation

5-HT release inhibitor

Potent blocker of BK_Ca channels

High affinity σ₂ agonist

PAF receptor antagonist

Selective M₄ antagonist

Potent, selective non-peptide AT₂ antagonist

D₃ agonist (D₃ ≥ D₂ > D₄)

Potent and selective CCK₂ antagonist

High affinity, selective σ₁ ligand

Selective 15-lipoxygenase inhibitor

EGFR-kinase inhibitor

Potent ErbB receptor family inhibitor

Selective non-peptide NPY Y₁ antagonist

Selective FGFR inhibitor

Broad spectrum MMP inhibitor

High affinity, selective D₄ agonist

Selective neuromedin B receptor antagonist (NMB-R, BB₁)

Potent and selective D₄ antagonist

Selective FGFR1 and -3 inhibitor

Potent N-type Ca²⁺ channel blocker

GRP (BB₂) and NMB (BB₁) receptor antagonist

Selective inhibitor of MEK1/2

Selective inhibitor of Chk1 and Wee1

Allosteric potentiator of A₁ receptors

Specific inhibitor of MEK

Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor

Disrupts interaction between GluR6 and PSD-95 PDZ1 domain

CNS stimulant, indirect monoamine agonist

M2 proton channel blocker

Antimicrobial that antagonizes NMDA receptors

Adenosine deaminase inhibitor

PDE inhibitor

CNS stimulant

GluR1 subunit C-terminus peptide analog. Analog of Cat. No. 1601

GluR1 subunit C-terminus peptide analog

Peptide inhibitor of GluR2 subunit binding to PICK1

Peptide inhibitor of GluR2 subunit binding to PICK1

Peptide inhibitor of GluR2 subunit binding to NSF. Reduces AMPA currents

Inactive control peptide for pep2-SVKI (Cat.No. 1597)

Peptide inhibitor of GluR2 subunit binding to GRIP, ABP and PICK1. Increases AMPA current amplitude

Inactive control peptide for pep2m (Cat.No. 1595)

Allosteric potentiator of AMPA receptor desensitization

Aspartic protease inhibitor

Inhibits laminin-mediated cell adhesion and migration

Selective Y₂ receptor agonist

Catalyzes ADP-ribosylation of G_i, G_o and G_t

Activator of caspase-3

Potent and selective CB₁ antagonist

Potent and selective FAK inhibitor

Potent and selective CK1ε and CK1δ inhibitor

Selective FAAH inhibitor

Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor

Presynaptic cholinergic modulator

Potent and selective α7 nAChR agonist

α7-selective agonist

Potent and selective MET inhibitor

Dual cdc7/cdk9 inhibitor. Also inhibits MK-2

Weak, selective GABA_B antagonist

Potent group I mGlu antagonist

Non-competitive NMDA receptor antagonist

Cholinesterase inhibitor

5-HT₃ agonist

Histone deacetylase inhibitor

α₁ agonist

Potent melatonin agonist

DA release inhibitor

GluR1/2 selective AMPA antagonist

Potent calcitonin receptor agonist; endogenous analog of human VIP

Protein kinase C activator

Selection of 5 phosphodiesterase inhibitors (Cat. Nos. 0915, 1504, 0415, 1349 and 1046)

Blocking peptide (phosphorylated) for anti-phospho-GluR1 (Ser⁸³¹) (Cat. No. 2041)

Blocking peptide (unphosphorylated) for anti-phospho-GluR1 (Ser⁸³¹) (Cat. No. 2041)

Glycogen synthase kinase-3 substrate (synthetic)

Blocking peptide (phosphorylated) for anti-phospho-NR2A (Ser¹²³²) (Cat. No. 2056)

Blocking peptide (unphosphorylated) for anti-phospho-NR2A (Ser¹²³²) (Cat. No. 2056)

Group III mGlu agonist

Selective ERβ antagonist

Cholinesterase inhibitor

Inhibitor of PI 3-kinase, mTOR and DNA-PK

PI 3-kinase inhibitor, more potent than LY 294002 (Cat.No. 1130)

Inhibits TNF-induced NF-κB activation

Selective IGF1R inhibitor

GABA_A receptor antagonist

Inhibitor of p53-mitochondrial binding

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Muscarinic agonist

Pim-1 kinase inhibitor

D₂-like antagonist

β₃ partial agonist

β₃ partial agonist. More active enantiomer of Cat. No. 0994

σ₁ selective ligand

5-HT₄ agonist. Also 5-HT₃ antagonist

Nootropic; modulates Na⁺-flux at AMPA receptors

Selective M₁ muscarinic antagonist

Antifibrotic agent; regulates cytokine levels in vivo

Dopamine agonist

MAO-A inhibitor

Cyclooxygenase (COX-1) inhibitor

P2Y ligand; displays mixed antagonism/potentiation

Potent PARP inhibitor

Antagonist at peripheral benzodiazepine receptors

Potent protein kinase A inhibitor

Selection of 5 PKA modulators (Cat. Nos. 1337, 1140, 1099, 1288 and 1603)

Protein kinase C inhibitor

Selective cell-permeable PKC inhibitor peptide (attached to vector)

Potent activator of protein kinase C

PKC ζ inhibitor peptide (attached to cell-permeable vector)

Cell-permeable protein kinase A inhibitor

Encephalitogenic myelin proteolipid fragment

Potent, selective α₁ antagonist

GCP II inhibitor

Competitive NMDA antagonist

Potent and selective 5-HT_1D agonist

Positive allosteric modulator of α7 nAChR; active in vivo

Highly selective 5-HT_1D agonist

Highly selective D₃ antagonist

5-HT_2C agonist and 5-HT_2A/2B partial agonist

Selective α7 nAChR agonist

Vascular K_ATP channel blocker

D₄ and 5-HT_2A antagonist; antipsychotic

Inhibitor of E-NTPDases

Slows neuronal Na⁺ channel inactivation

Commonly used laboratory reagent

Potent, selective Src inhibitor

Potent, selective Src inhibitor

Negative control for PP 2 (Cat. No. 1407)

Inhibits tyrosine kinase activity of pp60^c-src and pp60^v-src

P2 purinergic antagonist

P2X antagonist

Non-pungent vanilloid receptor agonist

Specific σ ligand, NMDA antagonist

Subtype-selective NR2C/NR2D antagonist

MT₂ antagonist

Potent, selective mGlu₈ agonist

Potent, selective P2X₁ antagonist

Competitive NR2A antagonist

Subtype-selective ERα agonist

IGF1R inhibitor

IκBα inhibitor

HMG-CoA reductase inhibitor

α₁ antagonist. MT₃ antagonist

Highly selective σ₁ agonist

GABA_A receptor positive allosteric modulator

Restores mutant p53 activity; induces apoptosis

Restores mutant p53 activity

Potentiates GABA_A receptor function

Prion protein fragment

Potent, reversible MAGL inhibitor

Antioxidant, anti-inflammatory and hypocholesterolemic agent

Potent β₂ agonist

D₂ receptor antagonist. Also 5-HT₃ and nAChR antagonists

Endogenous progesterone receptor agonist

β antagonist

Intermediate in lipid metabolism

Potentiates GABA_A receptor-mediated inhibition and inhibits glutamate receptor-mediated excitation

β antagonist

Propranolol metabolite

β antagonist. Less active enantiomer of Cat.No. 0624

β antagonist. More active enantiomer of Cat.No. 0624

Highly selective inhibitor of nNOS

Major endogenous prostanoid

Endogenous PPARγ agonist

High affinity H₃ ligand

Potent and selective P2Y₆ agonist

NTPDase 3 inhibitor

Non-selective NTPDase inhibitor

Selective A_2B antagonist

Potent, highly selective human A₃ receptor antagonist/inverse agonist

Potent, selective human A₃ receptor antagonist/inverse agonist

Selective human A_2B receptor antagonist; water-soluble

Potent and selective A₁ antagonist

Highly selective A_2B antagonist

Protein kinase C activator peptide (attached to cell permeable vector)

GPR119 receptor agonist

O-GlcNAcase and β-hexosaminidase inhibitor

Cyclin-dependent kinase inhibitor

Cyclin-dependent kinase inhibitor

H₁ receptor agonist

Inhibits NF-κB, prevents increase in NOS mRNA