All Products

Cat.No.

Product Name / Activity

Selective agonist for the GPR109B (HM74) receptor. Antilipolytic

K⁺ channel blocker (high conductance, Ca²⁺-dependent)

A₃ selective agonist

PDE inhibitor (non-selective)

Non-selective NMDA agonist

σ ligand, σ₁ > σ₂

PDE inhibitor (non-selective)

Cyclooxygenase inhibitor (COX-1 > COX-2)

Very selective β₂ antagonist

δ selective peptide antagonist

Potent H₂ antagonist, active in vivo

δ selective peptide antagonist

Estrogen receptor antagonist

Potent thromboxane receptor antagonist

Potent thromboxane A₂/TP receptor antagonist

Potent κ agonist

κ agonist, acts peripherally

β₃ agonist

Potent Bombesin/Gastrin releasing peptide antagonist

PDE4 inhibitor

β antagonist

Activates a novel cold receptor. Cooling agent

α₂ antagonist. Also I₂ ligand

Antioxidant and neuroprotective agent

Inhibits AMPA receptor desensitization

Open-channel blocker of AMPA currents; selective for non-GluR2-containing receptors

Fluorogenic granzyme B substrate

Non-competitive NMDA antagonist. Also σ ligand

NR2B-selective NMDA antagonist. Also σ agonist

Selective inhibitor of IKK

Prostacyclin (PGI₂) analog

Inhibitor of IKK-2

Standard H₃ and H₄ agonist (H₃ > H₄)

Highly selective α_2B antagonist

Selective iNOS inhibitor

Toll-like receptor 7 (TLR7) agonist

Standard H₃ agonist. Also H₄ agonist

Potent H₃ agonist, highly selective over H₄

Selective H₃ antagonist

Inhibitor of calcineurin-substrate association

Potent 5-HT uptake inhibitor. Also inhibits dopamine and noradrenalin uptake

Microtubule destabilizer

Subtype-selective GABA_A receptor positive allosteric modulator

GSK-3β inhibitor. Also inhibits other protein kinases

Protein kinase C activator

Cyclooxygenase inhibitor (COX-1 > COX-2)

5-HT_1A, 5-HT_1B and 5-HT_2C agonist

Potent inhibitor of Ins(1,4,5)P₃ 5-phosphatase. Metabolite of Cat. No. 1482

Ca²⁺ mobilizing second messenger

Endogenous peptide agonist

High affinity α4β2 and α6β2 subtype-selective agonist

Precursor to 5-Iodo-A-85380 (Cat. No. 1518)

High affinity melatonin agonist

Potent, competitive vanilloid receptor antagonist

Potent, selective H₃ antagonist

Potent, silent TRPV1 antagonist

High affinity TRPV1 agonist/partial agonist

Potent adenosine kinase inhibitor. Also inhibits nucleoside transporters and a range of other kinases

Highly potent, subtype-selective kainate agonist

Calcium ionophore

Calcium ionophore

Group I p21-activated kinase (PAK) inhibitor

Potent σ antagonist

Muscarinic antagonist

Selective 5-HT_1A agonist

Orally active, selective EGFR inhibitor

Potent ET_B antagonist

ET_B antagonist

Highly selective ET_B agonist

PDE4 inhibitor; antiulcer agent

5-HT_1B antagonist

Selective GABA_A agonist

iNOS inhibitor, acts arginine binding site

Standard selective β agonist

Ca²⁺ channel blocker (L-type)

Endogenous agonist for the transcription factor aryl hydrocarbon receptor

Potent caspase-3 inhibitor

Allosteric modulator of α7 nicotinic receptors