All Products

Cat.No.

Product Name / Activity

Antibody recognizing DARC

Endocytosis blocker

Selective CK1 inhibitor. Also inhibits TGF-βRI

Selective PC-PLC inhibitor

Inhibitor of tubulin polymerization. Antitumor in vivo

Prototypical δ agonist

Arrests cell cycle in G1 phase

Selective μ agonist

Muscarinic M₃ antagonist

Ca²⁺ release inhibitor

Death associated protein kinase substrate (synthetic)

γ-secretase inhibitor

Chemokine receptor 5 (CCR5) antagonist

M₃ receptor antagonist

RNA synthesis inhibitor

Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor

Allosteric modulator at mGlu₅

Activates Cl^- conductance and hIK1 K⁺ channels

Very potent, selective group II mGlu agonist. Also NMDA agonist

Selectively induces cancer cell apoptosis

AMPA antagonist/weak NMDA antagonist

Potent systemically active anticonvulsant. Racemate of Cat. No. 1395

Potent, selective mGlu_8a agonist

Selective blocker of VSAC/I_Cl,swell; inhibits glucose-stimulated insulin release

Endogenous CB₁ agonist

Selective Akt/PKB inhibitor

Intermediate in lipid metabolism

DNA methyltransferase inhibitor

Anticancer and antiviral agent; chemopreventive and pro-apoptotic

Selective δ agonist peptide

Selective insulin RTK activator

α-Mannosidase I inhibitor

Glucosidase I and II inhibitor

MAO-B inhibitor

Selective inhibitor of noradrenalin transporters

5-HT_2C antagonist

Synthetic vasopressin analog; V_1B and V₂ agonist

Selective, orally active CCK₁ receptor antagonist

Fluorogenic caspase substrate

Cell-permeable, irreversible caspase-3 inhibitor

Anti-inflammatory glucocorticoid

5-HT re-uptake inhibitor. Also stimulates 5-HT release

Potent, highly selective α₂ agonist. Active isomer of Cat. No. 2023

NMDA receptor antagonist

Allosteric potentiator at mGlu₅

Ornithine decarboxylase inhibitor

Diacyl glycerolacyltransferase 1 (DGAT-1) inhibitor

Broad spectrum glutamate receptor antagonist

MT₂ receptor antagonist

Ca²⁺ release inhibitor

Selective group I mGlu agonist

Selective group I mGlu agonist. Active enantiomer of Cat. No 0342

Inhibits biosynthesis of tetrahydrobiopterin and thus NOS

Acts at the benzodiazepine modulatory site

Blocks desensitization of AMPA receptors

N-myristoyltransferase-1 inhibitor; antiproliferative

Cell-permeable cAMP analog

Potent NMDA antagonist, acts glycine site

Sodium salt of Cat. No. 0286. Potent NMDA antagonist, acts glycine site

Spermine and spermidine acetyltransferase potentiator

Polyamine synthase inhibitor

High affinity inhibitor of 14.3.3 proteins; induces apoptosis

Selective D₁-like agonist

Antagonist for neuronal α4-containing nicotinic receptors

Partial α agonist. Non-selective

Partial α agonist. Non-selective

Binds to GABA_A receptor Cl^- channel; allosteric modulator of benzodiazepine site

EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake

Protein kinase C inhibitor

TrkB agonist

Component of Joro spider toxin

Adenosine uptake inhibitor

Ca²⁺ channel blocker (L-type)

Standard H₂ selective agonist

Neuroprotectant; protects against β-amyloid neurotoxicity

M₂-selective antagonist

Diacylglycerol kinase inhibitor

H₁ receptor antagonist

Binds to flavoproteins and inhibits NOS

NMDA antagonist, acts ion channel site

Selective irreversible κ antagonist

Non-selective opioid antagonist

A₁ selective antagonist

Adenosine transport inhibitor

Alcohol dehydrogenase inhibitor; displays a range of other activities

Maintains SH groups in the reduced state

Partial agonist at α7-containing receptors and antagonist at α4β2 neuronal nicotinic receptors

Water-soluble Hsp90 inhibitor

Benzodiazepine inverse agonist

Negative allosteric modulator at mGlu₅

Metabolically stable anandamide transport inhibitor

DNA-dependent protein kinase inhibitor

K⁺ channel blocker and potent ACh release enhancer

Nitric oxide spin trap; measures oxygen-centered free radicals

Potent, selective inhibitor of PDGFRβ

Solvent

Selective non-NMDA antagonist

Selective non-NMDA antagonist. Water-soluble salt of Cat. No. 0189

Selective 5-HT₂ agonist

α₁, β₁ and β₂ agonist

Selective RXR agonist

hERG channel blocker; inhibits rapid delayed rectifier K⁺ current (I_Kr)

Mixed 5-HT_2A/2C agonist

Potent, selective kainate agonist

Peripheral D₂-like antagonist

Endogenous agonist at dopamine D_1-5 receptors

Potent and selective AMPK inhibitor

α₁ antagonist

Highly potent H₁ antagonist. Also binds to H₄ receptor

Vitamin D₂ analog, VDR agonist

Antitumor antibiotic agent. Inhibits DNA topoisomerase II

A₁ selective antagonist

Selective δ agonist

Highly potent ERβ agonist

Blocker of K_V1.5 channel and I_Kur current

Inhibitor of histamine binding at the intracellular binding site

Dipeptidyl peptidase IV (DPP-IV) inhibitor

Caspase-3 inhibitor

Potent PARP inhibitor

Dual CK1/cdk inhibitor

Positive allosteric modulator of δ-containing GABA_A receptors

Selective δ agonist peptide

Adrenergic neurotoxin

High affinity ligand (σ₁ = σ₂)

Cyclooxygenase-2 (COX-2) inhibitor

Agonist selective for estrogen-related receptors ERRβ and ERRγ

Dynamin inhibitor

Cell-permeable dynamin inhibitor

Control peptide version of Cat. Nos. 1774 and 1775

Non-competitive dynamin inhibitor

Endogenous κ agonist

Endogenous κ agonist