Tocris offers a range of libraries/collections of exceptionally high quality ligands to suit your screening needs including an off-the-shelf range (Tocriscreen) and Customized Collections. In addition, we offer a range of Tocriset ligand sets designed to explore the pharmacology of specific receptors or cellular targets using conventional binding and functional assays.
| |
 |
 |
| What is it? |
A range of libraries/collections of Tocris ligands suitable for screening purposes. |
A set of Tocris ligands within a defined pharmacological or signaling area. |
| What can it be used for? |
To standardize/validate new screening assays.
To de-orphan receptors and identify interacting ligands.
|
To probe the pharmacology of a specific receptor target using subtype selective ligands.
To investigate the function of signal transduction cellular targets.
|
| Is it suitable for High Throuput Screening? |
Yes |
No |
| What is its format? |
96-well plate format in piercable silicone capped 1.4 ml tubes.
2 mg per well dry compound.
16 blank control wells included per 96-well plate.
|
3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration.
Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.
|
| What literature is available with each product? |
Full ISIS database and Excel file on CD-ROM includes structures, and chemical and pharmacological information. |
Accompanying booklet provides detailed solubility instructions including suitable solvents, and chemical and pharmacological information. |
| Detailed FAQ |
Click here |
Click here |
