Tocris Bioscience

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Product Pages Catalogue Numbers 1801 - 1900

Cat. No. Product Name & Pharmacological Action
1801WAY 161503 hydrochloride
Potent, selective 5-HT2C agonist
18022B-(SP)
Selective GSK-3 phosphopeptide substrate
1803ITE
Endogenous agonist for the transcription factor aryl hydrocarbon receptor
1804SR 2640 hydrochloride
Potent, selective LTD4 /LTE4 receptor antagonist
1805Gly-Pro-Arg-Pro
Inhibits fibrin polymerisation
1806SR 33805 oxalate
Ca2+ channel blocker; binds allosterically to distinct site on L-type channels
18072-Methoxyestradiol
Apoptotic and antiangiogenic agent
1808E-4031 dihydrochloride
K+ (HERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
1809Altanserin hydrochloride
5-HT2 receptor antagonist
1810Raclopride

Potent, selective D2/D3 antagonist

1811Modafinil
Psychostimulant
1813Indirubin-3'-oxime
GSK-3β inhibitor. Also inhibits other protein kinases
1814N-ArachidonylGABA
Inhibits pain in vivo
1815Palmitoylisopropylamide

Inhibitor of FAAH

1816ICI 63197
PDE4 inhibitor
1818Octreotide
sst2, sst3 and sst5 agonist
1819Demethylasterriquinone B1
Selective insulin RTK activator
1821YM 976
PDE4 inhibitor
1822AMPA Receptor TocrisetTM
Selection of 5 AMPA receptor ligands (Cat. Nos. 0254, 0306, 1044, 0713 and 1454)
1823NMDA Receptor - Glycine Site TocrisetTM
Selection of 5 NMDA receptor (glycine site) ligands (Cat. Nos. 0219, 0281, 0742, 1493 and 0237)
1824Kainate Receptor TocrisetTM
Selection of 5 kainate receptor ligands (Cat. Nos. 0222, 1107, 0903, 1045 and 1454)
1825Mixed NMDA Receptor TocrisetTM
Selection of 5 mixed NMDA receptor ligands (Cat. Nos. 0114, 0312, 0106, 0924 and 1241)
1826Group I mGlu Receptor TocrisetTM
Selection of 5 group I mGlu receptor ligands (Cat. Nos. 0805, 0188, 1237, 1212 and 0337)
1827Group II mGlu Receptor TocrisetTM
Selection of 5 group II mGlu receptor ligands (Cat. Nos. 1208, 0975, 1209, 0971 and 0337)
1828Group III mGlu Receptor TocrisetTM
Selection of 5 group III mGlu receptor ligands (Cat. Nos. 0103, 1220, 0972, 0803 and 1209)
1829Mixed mGlu Receptor TocrisetTM
Selection of 5 mixed mGlu receptor ligands (Cat. Nos. 0805, 0975, 0103, 0337 and 1209)
1830Excitatory Amino Acid Transporter Inhibitor TocrisetTM
Selection of 5 EAAT inhibitors (Cat. Nos. 0183, 0298, 1223, 0111 and 0903)
1831HS 014
Selective MC4 receptor antagonist
1832HS 024
Highly potent MC4 receptor antagonist
1835FRATide
GSK-3 inhibitor
1836Seglitide
sst2 and sst5 agonist
1838IRL-2500
Potent ETB antagonist
1839BIM 23127
NMB receptor antagonist. Also UT-II receptor antagonist
1840Fostriecin sodium salt
Potent PP2A and PP4 inhibitor
1842RHC 80267
Diacylglycerol lipase inhibitor. Weak inhibitor of PLC and PLA2
1843CYN 154806
Selective sst2 antagonist
1844BIM 23056
Somatostatin receptor ligand
1845Ac2-26
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
1846Ac2-12
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
1847Eticlopride hydrochloride
Selective D2/D3 antagonist
1849EMD 66684
Potent, selective non-peptide AT1 antagonist
1850Exo1
Inhibits Golgi-ER traffic; blocks exocytosis
1851Glucagon-like peptide 1 (1-37) (human, bovine, guinea pig, mouse, rat)
Endogenous pancreatic peptide
1852(S)-(-)-Blebbistatin
Selective inhibitor of myosin II. Active enantiomer
1853(R)-(+)-Blebbistatin
Inactive enantiomer of the myosin II inhibitor (±)-blebbistatin (Cat. No. 1760)
1854Ro 60-0175 fumarate
Potent, selective 5-HT2C agonist
1856L-165,041
Potent PPARδ agonist
1857Burimamide oxalate
Mixed H2/H3 antagonist
1858Impentamine dihydrobromide
Selective H3 antagonist
1860Eltoprazine hydrochloride
5-HT1 receptor agonist/partial agonist
1862PRIMA-1
Restores mutant p53 activity; induces apoptosis
1866MRS 1845
Potent SOC inhibitor; blocks capacitative Ca2+ entry
1867NSC 663284
Potent, selective Cdc25 phosphatase inhibitor
1868U0124
Inactive analogue of U0126 (Cat. No. 1144)
1869Ipsapirone
Selective 5-HT1A agonist
1870BTS
Selective inhibitor of skeletal muscle myosin II ATPase activity
1871α1-Adrenoceptor TocrisetTM
Selection of 5 α1-adrenoceptor ligands (Cat. Nos. 1052, 0888, 1006, 0946 and 0623)
1872α2-Adrenoceptor TocrisetTM
Selection of 5 α2-adrenoceptor ligands (Cat. Nos. 1030, 0425, 0928, 1133 and 0891)
1873β-Adrenoceptor Agonist TocrisetTM
Selection of 3 β-adrenoceptor agonists (Cat. Nos. 0948, 1747 and 1660)
1874β-Adrenoceptor Antagonist TocrisetTM
Selection of 3 β-adrenoceptor antagonists (Cat. Nos. 1024, 0821 and 1511)
1875Mixed Adrenergic TocrisetTM
Selection of 5 mixed adrenoceptor ligands (Cat. Nos. 0888, 0425, 1747, 0623 and 0952)
1876Histamine H3 Receptor TocrisetTM
Selection of 5 histamine H3 receptor ligands (Cat. Nos. 0729, 0569, 0752, 0779 and 0644)
1877Serotonin Uptake Inhibitor TocrisetTM
Selection of 5 serotonin uptake inhibitors (Cat. Nos. 0596, 1427, 0457, 0927 and 1033)
1878MAPK Cascade Inhibitor TocrisetTM
Selection of 5 MAPK cascade inhibitors (Cat. Nos. 1110, 1213, 1321, 1144 and 1202)
1879MAPK Inhibitor TocrisetTM
Selection of 5 MAPK inhibitors (Cat. Nos 1213, 1202, 1264, 1496 and 1144)
1880Mixed Kinase Inhibitor TocrisetTM
Selection of 5 mixed kinase inhibitors (Cat. Nos. 0741, 1277, 1288, 1289 and 1285)
1881Phosphodiesterase Inhibitor TocrisetTM
Selection of 5 phosphodiesterase inhibitors (Cat. Nos. 0915, 1504, 0415, 1349 and 1046)
1882PKA TocrisetTM
Selection of 5 PKA modulators (Cat. Nos. 1337, 1140, 1099, 1288 and 1603)
1883cGMP Dependent Kinase Inhibitor Peptide
Inhibitor of protein kinases G and A
1884[D-Trp7,9,10]-Substance P
Inhibits M1 ACh receptor activation of Gq/11
1885MLCK inhibitor peptide 18
Selective inhibitor of myosin light chain kinase
1886Neuropeptide SF (human)
Implicated in pain modulation and opioid function
1887PKC fragment (530-558)
Potent activator of protein kinase C
1889[Leu5]-Enkephalin
Endogenous opioid agonist peptide
1890Neuromedin C (porcine)
Mammalian bombesin-like peptide
1891Calcineurin Autoinhibitory Peptide
Selective calcineurin inhibitor
1892Amyloid b-Peptide (10-20) (human)
Amyloid β-peptide; substrate for MMP-2
1893Alytesin
Amphibian bombesin-like peptide
1894Amyloid β-Peptide (12-28) (human)
Amyloid β-peptide; minimum required for binding to brain proteins
1896Mastoparan X
G protein activator peptide
1897Angiotensin IV (human)
Agonist for the AT4 receptor
1898Guanylin (human)
Endogenous activator of intestinal guanylyl cyclase
1899Sarafotoxin S6a
Endothelin receptor agonist
1900[Ala107]-MBP (104-118)
Protein kinase C inhibitor
 
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