Tocris Bioscience

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Product Pages Catalogue Numbers 1401 - 1500

Cat. No. Product Name & Pharmacological Action
1401NU 1025
Potent PARP inhibitor
1402SB 203580 hydrochloride
Selective inhibitor of p38 MAPK; water-soluble
1403FPL 64176
Potent activator of L-type Ca2+ channels
1405(-)-Terreic acid
Selective inhibitor of BTK
1406Trichostatin A
Histone deacetylase inhibitor
1407PP 2
Potent, selective Src inhibitor
1408YM 022
Highly potent, selective non-peptide CCK2 antagonist
1409CGP 39551
Potent, selective and competitive NMDA antagonist. Brain penetrant in vivo
1410SDM25N hydrochloride
Potent, selective non-peptide δ antagonist
1411Noladin ether

Endogenous agonist for CB1

1412Chromanol 293B
IKs blocker. Also blocks ICFTR
1413NAS-181
Selective r5-HT1B antagonist. Active in vivo
1414Scopolamine hydrobromide

Non-selective muscarinic antagonist

14151400W dihydrochloride
Potent, highly selective iNOS inhibitor
1416Homoharringtonine
Inhibitor of protein synthesis. Antileukemic agent
1417Daidzein
Arrests cell cycle in G1 phase
1418Resveratrol
Cyclooxygenase inhibitor
1419Naloxone benzoylhydrazone
κ3 agonist. Antagonist at μ, δ, κ1 and ORL1
1420D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt
Potent inhibitor of Ins(1,4,5)P3 5-phosphatase. Metabolite of Cat. No. 1482
1421MAFP

Potent, irreversible anandamide amidase inhibitor

1422DCEBIO
Activates Cl- conductance and hIK1 K+ channels
1425(S)-(+)-Dimethindene maleate

M2-selective antagonist

1426PPT
Subtype-selective ERα agonist
1427Citalopram hydrobromide
Highly potent and selective 5-HT uptake inhibitor
1428Amyloid β-Peptide (1-42) (human)
Predominant amyloid β-protein fragment
1429Amyloid β-Peptide (25-35) (human)
Human amyloid β-protein fragment functionally required for neurotoxicity
1430DuP 697
Cyclooxygenase (COX-2) inhibitor
1431DPDPE
δ-receptor agonist
1435SQ 22536
Adenylyl cyclase inhibitor
1437D609
Selective PC-PLC inhibitor
1439Ruthenium Red
Non-selective Ca2+ channel blocker (N- and P-type)
1440BMY 14802 hydrochloride
Sigma antagonist. Antipsychotic agent
1441BMS 182874 hydrochloride
Highly selective, orally active non-peptide ETA antagonist
1442BMY 45778
Non-prostanoid prostacyclin IP receptor partial agonist
1443Metastin (human)
Potent, endogenous ligand for KISS1 receptor (hOT7T175, AXOR12 and GPR54)
1445N-Arachidonylglycine

Novel endocannabinoid. Suppresses pain in vivo

1446O-2093
Inhibitor of anandamide uptake
1447SKF 81297 hydrobromide

D1 agonist

1448Formoterol hemifumarate

Potent and selective b2 agonist

1450Galanin (1-15) (porcine, rat)
Galanin receptor agonist peptide
1451Galanin (2-29) (rat)
Selective GalR2 peptide agonist
1453Clemastine fumarate
H1 antagonist
1454GYKI 52466 hydrochloride
Selective non-competitive AMPA antagonist
1455Orexin A (human, rat, mouse)
Endogenous agonist at OX1 and OX2
1456Orexin B (human)
Endogenous agonist at OX1 and OX2
1457Orexin B (mouse)
Endogenous agonist for orexin receptors
1458DAPK Substrate Peptide
Death associated protein kinase substrate (synthetic)
1459SU 4312
Potent inhibitor of VEGFR tyrosine kinase
1460PACOCF3
Phospholipase A2 inhibitor
1461Linomide
Immunomodulator with antitumour properties
1462AACOCF3

Inhibits anandamide hydrolysis

1463Ghrelin (human)
Endogenous agonist for GHS receptor
1464TFLLR-NH2
PAR1-activating peptide
1465Ghrelin (rat)
Endogenous agonist for GHS receptor
1466PPAHV
Non-pungent vanilloid receptor agonist
1467Daunorubicin hydrochloride
Anticancer agent
1468SLIGRL-NH2
PAR2-activating peptide
1469CGP 37849
Potent selective NMDA antagonist. Orally active
1470Flecainide acetate
Cardiac Na+ channel blocker. Antiarrhythmic
1471Etomidate
GABA mimetic and GABA modulatory agent
1472Suramin hexasodium salt
Non-selective P2 antagonist
1475(-)-[3R,4S]-Chromanol 293B
IKs blocker. Enantiomer of (Cat. No. 1412)
1476Gap 27
Selective gap junction blocker
1477GR 127935 hydrochloride
Potent, selective 5-HT1B/1D antagonist
1479Mifepristone
Progesterone and glucocorticoid antagonist
1480FIT
Irreversible δ agonist
1481(-)-5'-DMH-CBD

Metabolically stable anandamide transport inhibitor

1482D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
Ca2+ mobilising second messenger
1483GR 89696 fumarate
Subtype-selective κ opioid agonist
1484Oleylethanolamide

Anandamide analogue, anorexic agent

1485DEA

Endogenous CB1 agonist

1486GR 231118
Potent NPY Y1 antagonist/NPY Y4 agonist. Binds to NPFF receptors
1487AY-NH2
Selective PAR4 agonist
1488tcY-NH2
Selective PAR4 antagonist
1489Mithramycin A
Anticancer antibiotic
1490MNI-caged-L-glutamate
Stable photoreleaser of L-glutamate
1493CGP 78608 hydrochloride
Potent, selective glycine-site NMDA antagonist
1494DPN
Highly potent ERβ agonist
1495Combretastatin A4

Inhibits tubulin polymerisation. Antitumour, antiangiogenic and antimetastatic

1496SP 600125
Novel and selective JNK inhibitor
1497Rimcazole dihydrochloride
σ2 antagonist. Also DAT inhibitor
1499CL 316243 disodium salt

Highly selective b3 agonist

1500BQ 788 sodium salt
Selective ETB antagonist
1495Combretastatin A4

Inhibits tubulin polymerisation. Antitumour, antiangiogenic and antimetastatic

 
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